Often, medical treatment of pancreatitis involves taking antibiotics. These drugs are used for chronic and acute form of the disease. In the chronic form of pancreatitis, antibiotics are used in the case of development of cholangitis and peripancreatitis. When they develop, prescribe medications such as cefuroxime intravenously or intramuscularly throughout the week 3 times / day for 1g, cefobide - twice a day at the same concentration or a weekly intramuscular course of ampiox for 2g intramuscularly four times a day.
If the long-term treatment of peripancreatitis with antibacterial therapy failed to achieve the expected results, this is the basis for suspicion of insensitive microflora, such as chlamydia and others. This position is the basis for smoking pancreatitis with antibiotics, such as sumamed and abaktal.
For a while, it was customary to prescribe them in an acute form for prevention, so to speak, with maintenance therapy. As an excuse for this method of treatment, data were given on t
he reduction of mortality in patients with a pancreatic patient. Also, the emphasis was on the higher mortality rates in case of an infected course of the disease compared with the lethality in the sterile, and therefore in the interval between the first and third weeks after the onset of acute pancreatitis, the use of antibiotics can indirectly reduce the lethality, preventing the development of infection in the inflamed pancreaticiron. However, after some time, during numerous studies of the influence of antibiotics on the pancreas, it turned out that although the incidence of infection in pancreatitis is reduced, which is confirmed by computer topography data, these drugs do not affect the overall mortality rate. Therefore, they are gradually stopped to be used for prophylaxis, and are prescribed only in the period of progressive organ failure, the development of the syndrome of a systemic inflammatory response, or in the deterioration of the clinical condition of a patient with signs of a beginning bacterial infection.
Conflicting data on whether antibiotics should be used in the treatment of pancreatitis or whether it is better to refuse such medication prophylaxis does not provide an opportunity to give an unambiguous answer to this question. Therefore, each doctor takes this decision himself, based on the patient's condition, on the nature and extent of the pancreatic gland.