Fortum: composition, form of release, indications for use, instructions, price

Fortum is a third generation antibiotic with a wide range of action. Antibacterial properties of this drug are actively used in different medical fields. One of the fields of application is dermatology.

Fortum is prescribed by injections for skin infections. This drug is potent with a mass of indications and contraindications. So do not experiment with it yourself. It should be used only with the doctor's prescription.

Features of the preparation

Fortum( Latin name - Fortum) is an antibiotic that is classed as a pharmacological group of cephalosporins. The main active microelement is ceftazidime( latin - Ceftazidime) in the form of pentahydrate.

Fortum( photo)

Dosage forms

Produced by Fortum powder for the preparation of solutions intended for intravenous, intramuscular injections. It is usually white, but may have a yellowish tinge.

Powdered mass is packed by manufacturers in glass bottles of 1/4, 1/2, 1 and 2 grams. Vials are individually packed in paper bundles

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Composition Fortum

The main active component of Fortum is ceftazidime pentahydrate. Additional substances - sodium carbonate and carbon dioxide.

Price

The cost of the drug in pharmacies is set taking into account its dosage. Buy it can be at a price ranging from 180 to 660 rubles.

The drug has bactericidal and antimicrobial properties. The mechanism of action of Fortum is the ability to break the cell walls of pathogenic microorganisms, which leads to their death.

Pharmacodynamics

The spectrum of action of the drug extends to gram-positive, gram-negative and anaerobic bacteria. Resistant to its action methicillin-resistant staphylococci.

Pharmacokinetics

After the intramuscular injection in the blood, its therapeutic concentration is observed in a few minutes. It lasts up to 12 hours.

The active substance, which has a harmful effect on foreign aggressive microorganisms, penetrates into the heart tissue, bone tissue, sputum, bile, intraocular fluid, synovial, pleural, peritoneal fluid. The medicine is able to penetrate the placenta. Ceftazidime is found in breast milk.

About 90% of the drug is excreted within a day from the body with the help of the kidneys, the rest - with bile.

Indications

In dermatology Fortum is used to treat such skin infections as:

  • erysipelas
  • phlegmon
  • peritonitis
  • ecthima
  • mastitis
  • wound infections
  • skin ulcer

In other areas of medicine:

Scope Diseases
Infectious diseases of the respiratory system Bronchitis, pneumonia, pleural empyema, infected bronchiectasis, lung abscess and others
ENT infections Otitis media of the middle ear, external malignant otitis, sinusitis and others
Infectious diseases of the urinary system Pyelitis, pyelonephritis, cystitis, prostatitis, urethritis, renal abscess, infections with kidney and bladder stones found
Joint and bone infections Septic arthritis, osteomyelitis
Gastrointestinal infections Gallbladder empyema, cholangitis, cholecystitis, peritonitis, retroperitoneal abscess, enterocolitis, diverticulitis
Sexual infection Gonorrhea
Other diseases Dialysis related infections, meningitis, sepsis

Instruction for use

The drug is intended for intramuscular and intravenous administration. Dose and treatment is calculated by the attending physician, taking into account the complexity of the course of the disease, the age of the patient and the condition of his kidneys.

To prepare injection solutions, use a solution of 5% glucose or sodium chloride 0.9%.For intramuscular injections, lidocaine 0.5% or 1% is usually used.

Adults

Patients are injected from 1 to 6 g of the drug per day for 2 to 3 times. According to an individual scheme, a doctor can prescribe injections according to one of the following schemes:

  • 1 gram of Fortum every 8 hours
  • 2 grams of Fortum every 12 hours

For a complex course of the disease or concomitant immunodeficiency, a daily dose of 6 grams is allowed for adult patients.

For children and newborns

  • For newborn babies and infants for up to 2 months, the drug is prescribed based on body weight - from 25 to 60 mg per kilogram of body weight. This daily dose is divided into two injections.
  • For children older than two months of age, the Fortum daily norm is 30 to 100 mg per kilogram of body weight and is intended for 2 to 3 injections. The norm can be increased to 150 mg per kilogram of body weight on an individual basis with meningitis, cystic fibrosis and weak immunity.

In pregnancy and lactation

If there is a strong indication, it is possible to prescribe the drug to women in the first weeks of pregnancy and nursing mothers.

Contraindications

The drug has a number of contraindications:

  • intolerance of drug components
  • renal failure
  • colitis
  • increased risk of reducing blood clotting

Side effects

Possible adverse effects of the drug:

Organs and body systems Possible side effects
Digestive system Diarrhea, nausea, vomiting, jaundice, abdominal pain, candidiasis of the oral mucosa and pharynx
Hematopoietic system Leukopenia, neutropenia, thrombocytosis, eosinophilia, hemolytic anemia( erythrocyte destruction, thrombocytopenia, lymphocytosis, agranulocytosis
CNS Change in sensations of taste, tremor, dizziness, headache, encephalopathy, myoclonia, coma
Excretory system Development of renal pathology, Creatine and urea blood levels
Allergic manifestations Urticaria, fever, Quincke's edema, toxic epidermal necrolysis, lowering of pressure, bronchospasm
Local reactions Swelling, pain, burning at the injection site, phlebitis, thrombophlebitis
Other possible problems Vaginitis candidiasis, indirect Coombs reaction

Special instructions

  • If undesirable side effects occur, the drug should be discontinued.
  • In case of renal failure, the dose calculated per day should be reduced. This is due to the fact that a large percentage of the drug is excreted from the body by the kidneys.
  • With prolonged use of Fortum, the growth of resistant microorganisms may increase. In this case, the use of the drug is suspended.

Interaction with other drugs

  • Fortum is not prescribed with nephrotoxic drugs, since the combination of these drugs has a negative impact on the kidneys.
  • The risk of toxic effects on the kidneys increases with the interaction of Fortum with loop diuretics, aminoglycosides, Vancomycin, and Clindamycin.
  • You can not use sodium bicarbonate to prepare the Fortum infusion solution.
  • Do not concurrent use for therapeutic purposes of Fortum in conjunction with Heparin, Chloramphenicol.

Reviews

On reviews of patients who have been treated with Fortum, the drug is effective where other drugs can not cope.

Doctors say that the drug is used exclusively in hospital under the supervision of a treating specialist, since the drug has a number of contraindications and can cause serious side effects.

Analogs

Drugs that have a Fortum similar scope and structure:

  • Ceftazidime
  • Ceftazidime-Akos
  • Vitsef
  • Ceftazidime Kabi
  • Ceftazidime Alpes
  • Ceftazidime Sandoz
  • Tizim
  • Ceftazidime-Dzhodas
  • Orzid
  • Ceftazidime Pfizer
  • Tsefzid
  • Tseftidin
  • Fortazim
  • Tazitsef
  • Bestum
  • Kefadim
  • Laurazidim

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