Alerzin is an antihistamine antiallergic medicine that acts mainly on the peripheral nerve endings. The product is manufactured by the Hungarian company Aegis, the effect lasts 24 hours. About instructions for use for children and adults Alerzin, its price, analogs and reviews about it will tell you today in detail.
Features of the drug
The active ingredient of the drug is levocetirizine, active against allergic rhinitis, idiopathic urticaria.
Composition Alerzin
Drops Alersin contains:
- levocetirizine in 1 ml contains 5 mg;
- of the auxiliary constituents accounts for a large proportion of glycerol, saccharin Na, Na trihydrate, E 218, E 216.
Preparation in tablets:
- 1 pc.5 mg of levocetirizine;
- of the additional ingredients is mainly cellulose, lactose.
Dosage forms
Manufacturer - Egis( Hungary), the price is:
- blisters 7 tablets - 50 UAH;
- blisters 14 tablets - 84 UAH;
- drops of 20 ml - 125 UAH.
Pharmacological action
Levocetirizine is a left-sided structural isomer of cetirizine. Has antipruritic effect, acts as a decongestant, eliminates inflammation.
Pharmacodynamics
Alerzine is an antihistamine drug that blocks peripheral histamine receptors. Levocetirizine reduces the permeability of blood vessels, reduces the production of inflammatory factors.
Pharmacokinetics
In 50% of patients, Alurzin's action is manifested 15 minutes after the use of the drug. In an hour, the effect of Alerzin is observed in 95% of patients.
The duration of the effect of levocetirizine is 24 hours. Levocetirizine is excreted mainly by the kidneys for 96 hours.
Indications
The agent is used to treat:
- pollinosis;
- of allergic rhinitis;
- urticaria( including cold, thermal, cholinergic);
- dermatosis with a rash, itching, caused by allergies.
Instruction for use
- Alerzine in tablets is not used in children under 6 years due to the impossibility of dosing.
- For children from 6 to 6 years of age, the drug is prescribed in drops.
Tablets
Adults and children after 6 years drink one tablet in 24 hours, regardless of eating, with water.
Drops
Drops accept:
- from 6 to 12 months.- 5 cap.per day;
- 1 year - 6 years - 5 cap.2 times / day;
- adults take 20 caps.1 time / day.
Adjustment from the creatinine clearance dose:
- if creatinine clearance is> 30-49 ml / min, take 5 mg 1 time / 2 days;
- & lt;30 ml per minute - 5 mg 1 time / 3 days;
Contraindications
Alerzine is contraindicated for admission:
- individual sensitivity;
- deficiency of lactase;
- impaired glucose uptake;
- complicated forms of renal failure;
- during pregnancy, lactation;
- earlier 6 years for tablets;
- up to 6 months - for droplets for oral administration.
Side effects of
Alerzin is well tolerated. Despite a representative list of contraindications, negative effects are noted rarely and when the drug is withdrawn disappear. If medication occurs, stop taking medication.
Side effects manifest themselves mainly from the psyche, cardiac, nervous system, changes are manifested in the work of the immune system, respiratory organs. The list of side effects includes:
- sleep disturbance - drowsiness or insomnia;
- excitement;
- headache;
- hallucinations;
- fainting;
- tremor;
- tachycardia;
- vagueness of vision;
- shortness of breath;
- dry mouth;
- vomiting;
- urticaria;
- hepatitis;
- muscle pain.
Special instructions
- The appointment of persons suffering from kidney failure requires dosage adjustment
- Alerzine increases the retention of urine. This should also be taken into account when assigning a dose for diseases accompanied by a delay in urine - with hyperplasia of the prostate, spinal cord injury.
- When pregnancy and lactation is not applied. To the components of drops Alerzin E218.In rare cases, E216 is allergic.
In case of an overdose of Alerzin, drowsiness is noted, sometimes - severe anxiety, excitement, sharply turning into a hindered state, drowsiness.
Interaction of
- Alerzin is allowed to be used simultaneously with antibiotics such as azithromycin, erythromycin, antifungal agent ketoconazole, adrenomimetic pseudoephedrine.
- Caution is used when taking medication with sedatives due to the possibility of increased sedation. It is undesirable to take the drug with alcohol.
- Although Alerzin does not enhance the effect of alcohol, with the combination of these substances, an additional negative effect of ethyl alcohol on the nervous system can be noted. Receiving Alerzin with food slightly reduces the effectiveness of the drug: without affecting the degree of absorption, food reduces the rate of drug intake into the blood.
Reviews
Drops Alerzin, according to the parents, are good for atopic dermatitis, manifestations of urticaria in young children. The effect of using the drug occurs quickly and is not retained after the withdrawal of the drug.
Among consumers' reviews there is also a more restrained attitude towards the drug. Among the shortcomings of the means indicated inadequate efficiency, high cost.
Analogs
Analogs( synonyms) of Alerzin for the active substance are Aleron, Xizal, Tsetril, Glencet. Analogues on the effect of the action - Zirtek, Zodak, Tsetrin, Cetirinax.
About Alerzin analogues, various allergy pills, will tell this video: