Suprax is an antibacterial agent available in various forms. This is a semi-synthetic cephalosporin antibiotic of the 3rd generation. Oppresses the synthesis of the cell membrane, is resistant to the action of lactamases, which are produced by most bacteria.
Composition, form, package
Capsules with a yellow lid and a former casing of 200 mg each contain a mixture of granules and powder. Capsules of 400 mg each have a purple cap and a white body. The last one shows the code H808.
Excipients are: silicon dioxide, magnesium, azorubin and carboxymethylcellulose. The shell is made of titanium dioxide, dyes and gelatin. In one carton pack contains 6 capsules placed in a cellular contour package.
Granules for the preparation of the suspension have 100 mg of active substance. Excipients are sodium benzonate, sucrose, flavor, yellow resin. Granules are produced for the preparation of a suspension in bottles with a dark glass of 60 ml.
Includes dosage spoon. After dilution, the suspension is almost white with a sweet strawberry taste. In all forms the principal antibacterial agent is cefixime.
Antibiotic is available in Jordan by GEDEON RICHTER
Indications for use
Suprax is prescribed for diseases caused by bacterial infection. It can effectively cure:
- angina and flu,
The main group of contraindications is the increased sensitivity of the body to drugs cephalosporin and penicillin group. With special care is assigned to babies up to 6 months old, elderly people, people with pseudomembranous colitis and kidney failure. For capsules, contraindications are children under 12 years of age.
Mechanism of action
Suprax is the first antibiotic of the third generation of the ciphalosporin group, which is used for internal use. Bactericidal mechanism is realized due to inhibition of the formation of the walls of pathogens of the disease.
Unlike other similar drugs, Suprax is resistant to enzymes of bacteria that destroy the antibiotic.
The bioavailability of the antibiotic is about 50%.Food does not reduce this figure, but by several units lengthens the time to reach the maximum amount in biological fluids. Among other similar drugs, this drug has a long half-life. Due to this, it is taken once a day. It is very convenient for treating babies.
The medicine perfectly penetrates into the focus of infection development - in the middle ear, tonsils, sinuses of the nose. With urine, 50% of the unchanged drug is excreted. Therefore, Suprax can be used to treat infections of the urogenital tract.10% is excreted with bile.
Instruction for use
These are shown to persons with a weight greater than 50 kg and age from 12 years. Assigned to 400 mg once a day. With gonorrhea occurring without complications, 400 mg 1 time is prescribed. The duration of taking the drug is 7-10 days. With infectious lesions, the course should be no less than 10 days. Patients with renal dysfunction with KK less than 60 ml / min, the drug is administered as a suspension.
For children under 12 years of age, the dose is selected depending on the weight: 8 mg / kg once a day or 4 mg / kg every 12 hours. Children from 5-12 years can drink no more than 10 ml per day, from 2-4 years - 5 ml, up to a year - 4 ml. The average duration is 7-10 days.
Side effects of
Skin allergic manifestations may appear:
- skin hyperemia,
- multiform exudative erythema.
Other systems can also react: headache, tinnitus, vaginitis, urinary system dysfunction, nausea, dysbacteriosis, jaundice, anemia, thrombocytopenia. On the part of laboratory indicators, there was an increase in liver transaminase activity, an increase in urea nitrogen, an increase in prothrombin time.
Other adverse events include the development of hypovitaminosis B, the appearance of dyspnea and candidiasis.
As the dose increases, side effects, especially on the part of the digestive tract, can be intensified. Treatment is carried out by washing, supporting therapy. It should be noted that peritoneal dialysis and hemodialysis are ineffective.
If necessary, antihistamines, glucocorticoids, pressor amines and transfusion of infusion solutions may be prescribed.
Capsules and suspension may be used only if the intended benefit to the mother is higher than the risk to which the fetus may be exposed. During the period of taking the medicine, it is recommended to interrupt breastfeeding.
Allopurinol, diuretics delay the excretion of cefixil by the kidneys. This increases the toxicity of the drug. Supraks reduces the prothrombin index and leads to an increase in the effect of indirect anticoagulants. Slow down the process of absorption of the drug can be drugs that contain magnesium, aluminum hydroxide.
If the kidneys or people on hemodialysis are disrupted, the daily dose is reduced by 25%.
Reviews about the drug
According to reviews, the drug is prescribed for various bacterial infections, enlarged lymph nodes. Assign more often than once a day, but children are recommended to split the dose into two divided doses.
Prices for Supraks
The current prices in Moscow start at 499 rubles. There are medicines in almost all pharmacies. More expensive capsules. Their cost starts from 620 rubles. The maximum threshold is 1240 rubles.
Structural inexpensive analogues:
- Cefaral Solutab,
- C ideodexor
Synonyms of medication
Read more about the analogues of the drug in our video:
Terms of dispensing from pharmacies
It is released by prescription.
Storage conditions and shelf life
Suprax is stored at a temperature of 15-25 degrees. Shelf life - 3 years. The finished suspension can be stored for no longer than 14 days.