Podophillin: indications, instructions for use, price of solution, reviews, analogues

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Anti-tumor agent. It is applied topically for the treatment of skin surfaces and mucous membranes.

Composition, form and packaging

Manufacturer produces the drug in two forms:

• powder, which is used for the preparation of solutions;
• is ready to use solution.

The main active substance is podophyllotoxin. Excipients: a- and b-Pelttines.

Manufacturer

Means of import origin, produced in European countries.

Indications for use

The agent is prescribed for such disorders:

• of the papilloma in the bladder region,
• benign formations on the inner surface of the bladder( on the mucosa) - those that are protruding above the surface in the form of nodules;
• benign laryngeal tumor,
• laryngeal papillomatosis,
• are used in cases of prevention of recurrence after electrocoagulation with papillomas,
• is used to control genital warts.

Contraindications

This:

• can not be used for children under the age of one year,
• also does not apply the drug in pregnancy,
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• otherwise the drug is not prescribed if the patient has a negative reaction to its constituents.

Pharmacological action

The agent causes a retarding effect on the growth of benign formations and papillomas. Therefore, its main action is defined as antitumor.

The effect is due to the fact that the active substance has the following properties:

• to suppress processes in tissues that increase the number of cells;
• damaging cells of formations,
• blocking cell division.

Instructions for use: Podofillina: dosage

For children and adults, the remedy is used to solve papillomas. There is some difference in the recommendations for different ages.

For adults, podophyllin is used as a suspension( 12%, 8%, 4%, 1%). If necessary, a catheter is used in the bladder. The suspension is prepared on a petrolatum oil.

Dose per treatment: 100 ml, time of suspension in the bladder 40 min or up to two hours. Between the procedures make a break for 7 days.

If manipulations are performed in patients of childhood, lubrication of the mucosa is done after removal by papillomas. The procedures are performed for 14 days at intervals of every other day. For lubrication apply alcohol solution( 15%).

Side effects of

When used for the treatment of agents with podophylline, such negative reactions are possible:

• in the control of papillomas in the larynx:
  • gastrointestinal malfunction,
  • vomiting,
  • feeling of nausea;
• with bladder manipulation:
  • discomfort during urination:
    • pain,
    • more frequent urge;
  • burning in the area of ​​the bladder.

Overdose

Overdose may occur if the product is used.

Signs of this phenomenon are

• appearance of sores on the oral mucosa,
• nausea,
• diarrhea,
• vomiting,
• myelosuppression,
• fever.

If an overdose occurs, then the remedial action must be taken.

If you get into the area of ​​the gastrointestinal tract( accidentally), you need to do a gastric lavage. If there is an excessive ingestion of the drug on the skin, then wash the surface with water using soap.

Specialists, if necessary, perform symptomatic therapy.

Special instructions

Do not allow the product to penetrate the eye mucosa, therefore eye protection must be worn when preparing solutions( connecting powder with other substances).

Drug Interaction

Specialists have not identified any interaction of the drug with other drugs during their joint application.

Reviews

Users note the effectiveness of the drug in the fight against papillomas. Also allocated podophyllin as a drug, which in comparison with its analogs causes fewer side effects.

Price Podofillina

The cost of the bottle, capacity of 3.5 ml in pharmacies ranges between 500 ÷ 800 rubles. But at present, the drug on the websites of pharmacies is not offered, it is difficult to find. On sale there are synonyms and analogues of the facility.

Analogues

Drugs that have a similar effect( similar), but are based on other active substances:

• gikamtin,
• reflex,
• onkaspar,
• sehydrin,
• velcade.

Synonyms for medication

Drugs that contain the same active ingredient:

• condylin,
• vartek.

Conditions for dispensing from pharmacies

The product is dispensed without a prescription.

Storage conditions and expiration date

The storage time of the preparation depends on the form of preparation:

• oil suspensions can last no more than two weeks,
• alcohol solutions are stored for up to three days.

Drugs should be kept in a dry place( in a dark place) at room temperature.