The pharmacotherapeutic group defines Sanguirithrin for antiseptic and disinfectant. Today we will tell you about it.
Features of the preparation
The antimicrobial activity of the drug gave him a wide spectrum of activity, he is subject to:
- gram-positive and gram-negative bacteria;
- micellar fungi and yeast;
- antibiotic-resistant species of microorganisms.
At acceptable therapeutic doses, it can stop the growth of bacteria.
Sanguirythrin( photo)
Dosage forms
The drug is released freely, without a prescription. Cardboard packaging reliably protects the liquid from exposure to light. Keep it up to + 25, not allowing children to have access to it. The drug is produced in the form of tablets, in vials and 0.5% liniment( ointment).
Composition of Sanguirithrina
Sanguitrytrine originates from its origins to the herb of the heart-shaped and the small-family poppy family( Papaveraceae). Sangviritrin is a mix of bisulfates, similar in structure and function to the alkaloids of sanguinarine and chelerythrine.
Price
- Price of the solution 50 ml - from 168 rubles.,
- tablets 5 mg 30 pcs.- from 87 rubles.,
- liniment 0,5% - from 167 rubles.
Pharmacological action
Sangviritrin is an antimicrobial drug that is applied topically and topically.
Pharmacodynamics
The drug has a wide spectrum of action: it affects gram-negative and gram-positive bacteria, antibiotic-resistant strains, yeast-like and mold fungi. The main action in the administration of therapeutic doses is bacteriostatic.
The whole process is due to the suppression of bacterial nuclease and impaired permeability of cell membranes. There is a change in the structure of the nucleotide.
Pharmacokinetics
The entire range of drug actions is associated with the functionality of individual components and it is not possible to conduct kinetic observations. It is difficult to keep track of all components at the same time using markers and bio-studies.
Indications
- Sanguirithrin is used prophylactically in neonates to prevent purulent-inflammatory skin diseases.
- Surgical patients are treated with a surface to prevent wound infection.
- For the treatment of sanguirithrin is used for infectious and inflammatory diseases that occur on the skin and mucous membranes caused by bacteria and fungi.
- In dentistry, the drug helps with stomatitis and periodontitis and other lesions of the oral mucosa.
- ENT doctors recommend Sanguirythrin for diseases of the middle and outer ear, with angina.
- Surgeons use a drug to treat infected burns that do not heal wounds and ulcers for a long time.
- Gynecology resorts to Sangviritrin in the erosion of the cervix, endocervicitis, vaginitis, colpitis.
- Dermatologists have found the use of the drug in the treatment of pyoderma and dermatomycosis, superficial blastomycosis.
- Also used for brain encephalopathy,
Instruction for use
The drug does not affect the ability to control mechanisms and drive vehicles. The drug is used topically and externally.
Adult
- For the treatment of periodontitis , thin turuns, moistened in a pure preparation or with its aqueous solution, are inserted into the gingival pockets for 20 minutes. The solution is prepared immediately before use: dilute 1 teaspoon in 200 ml of boiled water at room temperature. This procedure is recommended every day or every other day. The course is recommended for 4 to 6 procedures.
- For stomatitis , the drug is applied to the affected areas 2-3 times a day for 3-5 days.
- With tonsillitis , the tonsils are treated once a day for 2-5 days. Gargles are useful for adults and children over 5 years. They are carried out 3 to 5 times a day. The course of treatment can last up to 7 days.
- With external otitis , turundas are injected into the ear canal. They are wetted in the preparation and left for 10 minutes. The procedure is carried out 2-3 times a day. Treatment takes 2 weeks. Chronic suppurative otitis media is treated by instillation of 5-8 drops of the drug 2-3 times a day.
- If the wounds do not heal , then they are treated with a gauze swab, from a sterile material, richly moistened with the drug, then covered with a sterile napkin and apply a fixative bandage. This is a good preventive against purulent-inflammatory complications. The dressing is not changed for 3-4 days, and then re-processed and apply a sterile bandage, not wetting it. The course of procedures depends on the speed of wound healing and is within 7-10 days.
- When gynecological diseases do syringing, irrigation and lotions are carried out with a warm aqueous solution of Sangviritrine daily 2 times a day. The course takes 5-10 procedures.
- Dermatological problems of are treated by applying bandages or by lubricating the affected area daily up to 2 times a day. The duration and duration of treatment is affected by the nature and severity of the disease.
For children
- For children, the drug can be used from birth. Skin folds are processed up to 2 times a day during the first 5 days of life with a sterile cotton swab.
- After 5 years, children with stomatitis are rinsed with a warm water solution. Up to 5 years, treat mucous with the same solution.
- With a chronic average otitis purulent form instill a solution of 1-2 drops several times a day.
In pregnancy and lactation,
Women can use the drug before and during the puerperium.
Contraindications
Contraindications to the use of Sanguirithrin are:
- hypersensitivity to components;
- skin lesions caused by fungus with manifestations of foci of eczema;
- diseases of the excretory system with impaired function.
Side effects of
- From the side of the immune system, allergic reactions and redness are possible.
- When used on the mucous membrane of the mouth, bitterness occurs, and on the wound surface there may be a brief burning sensation.
- Some patients complain of nausea and abdominal pain, sometimes vomiting occurs.
Special instructions
Avoid contact with eyes. Otherwise, rinse thoroughly with plenty of water. Side effects may increase with greater use of the drug.
Interaction with other medications
It is possible to use Sanguirithrin along with topical anesthetics such as Promecaine and Trimecaine.
Reviews
- Margarita: "Specific taste repels the administration of the drug, but the rapid elimination of the first symptoms stimulates rinses."
- Cyril: "Severe burns were infected, the bandages were bandaged and the medication was taken internally. The infection went away and the tissue quickly healed. "
- Olga: "Infection and inflammation in the oral cavity relieves for 2 days."
Analogs
- Among the analogues of Sanguirithrin, Galenophyllipt can be distinguished. It is a good antiseptic and anti-inflammatory. Suitable for topical application in the treatment of wounds of various origin and burns. The composition contains chlorophyllipt and a complex of essential oils, which makes it more effective. Its positive aspect is the natural composition, but it can be dangerous when allergic to components. Of the minuses - the drying of the mucous membranes with prolonged use.
- Fukortzin can also be referred to analogues.
Pro Sangviritrin and other drugs for gargling in children, Dr. Komarovsky will tell in this video: