The Urerek is classified as a high-selective blocker of α1-adrenergic receptors. The medicine has found wide application in the therapy of prostatitis and benign prostatic hyperplasia.
Form release, formulation and packaging
The drug is produced in the form of hard capsules of white color with a yellowish tinge. Each capsule is filled with a fine crystalline powder. The drug is released at 4 and 8 mg. Capsules are packaged in blisters of 5 and 10 pieces. Up to 20 blisters can be stored in the package.
Photo medication Urerek 4 mg
The main ingredient of the drug is silodosin. Among the auxiliary ingredients are:
- Pregelatinized starch;
- Magnesium stearate;
- Mannitol;
- Sodium lauryl sulfate.
The gelatin capsules contain gelatin, titanium dioxide, iron oxide.
Manufacturer
Urerek is produced by LLC "Rusfic", which is a representative of the group of companies Recordati SPA( Italy).
Indications for use
The drug is prescribed as a complex therapy for conditions such as benign prostatic hyperplasia and prostatitis.
Contraindications
Refuse to take medication is recommended in the following situations:
- Age of the patient under 18 years of age;
- A history of severe hepatic or renal insufficiency;
- In the presence of hypersensitivity to components;
- With caution should be used for kidney failure of moderate severity.
Mechanism of action of the preparation
The Urerek is classified as a group of highly selective α 1 -adrenoreceptor blockers.
The drug simultaneously leads to a decrease in the severity of the symptoms of obstruction and irritation that occur against the background of the development of benign prostatic hyperplasia.
High affinity for α1-adrenergic receptors, which are located in the urinary tract, can prevent an increase in blood pressure in patients with normal initial BP.
Drug instruction manual Urerek
The drug is taken orally 8 mg once a day during meals. It is necessary to swallow the capsule whole, squeezed with a small amount of water. Urorek must be taken every day at the same time.
In case of impaired renal function, the drug is prescribed in the following dosage:
- In mild failure form, when the creatinine clearance value is between 50 and 80 ml / min, the dose may not be adjusted;
- In the state of moderate severity, when the clearance value is within 30-50 ml / min, it is necessary to take 4 mg of the drug during the first 7 days. If the Urerek is well tolerated, then the dosage is raised to therapeutic;
- In severe forms of impaired renal function, prescribing is not recommended.
In people who have a history of mild to moderate liver failure, the dose is not adjusted. Prescribe medication to patients with severe forms of liver dysfunction should not, because there is no information on the use of the drug in this pathology.
Side effects of
Taking medication can provoke the development of the following symptoms:
- The onset of erectile dysfunction;
- Decreased libido;
- Appearance of orthostatic hypotension;
- Anejaculation;
- Dryness in the oral cavity;
- Feeling of nasal congestion, which develops on the principle of allergic rhinitis;
- Nausea, diarrhea;
- The appearance of dizziness.
Overdose
When the therapeutic dose is exceeded, hypotension develops against a background of compensatory tachycardia.
Therapy of this condition involves washing the stomach, the appointment of enterosorbents, laxatives. Symptomatic treatment is carried out, which consists in increasing bcc, taking vasoconstrictive drugs.
Special instructions
Patients who have an orthostatic hypotension in a history do not recommend the use of silodosin. When the first symptoms of a decrease in pressure( dizziness, general weakness) should be taken horizontally. It is necessary to lie until the symptoms disappear completely.
Benign hyperplasia and prostate cancer have similar symptoms. Therefore, before the appointment of Urereka, one must undergo a comprehensive diagnosis in order to exclude the development of a malignant tumor.
Against the background of silodosin therapy, there is often a decrease in sperm production during orgasm. This can negatively affect male fertility. However, the symptom completely disappears after the drug is discontinued.
To exclude complications during an operation for excising cataracts, it is necessary to stop taking α1-blockers 10-15 days before the proposed date of surgery.
If a patient has a symptomatic of orthostatic hypotension, then it is necessary to abandon the management of transport and work requiring increased concentration of attention.
Compatibility of
Silodosin should not be taken concomitantly with other α1-adrenoreceptor blockers. Otherwise, the effect of drugs is potentiated.
Within the framework of joint use with inhibitors of the isoenzyme CYP3A4, an increase in the concentration of Uroreka occurs. Means that inhibit PDE5 can lead to dizziness when used concomitantly with an α 1 -adrenoreceptor blocker.
Drugs with an antihypertensive effect lead to an increase in orthostatic hypotension, so they should not be used during treatment with Urorecom.
Comments of patients and doctors
Anton, 37, Moscow:
Urorek helped to cope with an old prostatitis. Took part in the complex treatment. The pain syndrome during urination passed after 2 weeks of use. In the first 3 days there was diarrhea, but quickly passed.
Andrei Ivanovich, 47, St. Petersburg:
Used Urerek for 2 months to cure prostatitis. The drug is affordable, effective. A week later, I noticed an improvement in the condition. The drug is well tolerated - there were no side effects.
Egor, 33, Samara:
After the course of Urorec, urination normalized, the prostate size decreased. At the beginning of treatment, the pressure decreased, but after 5 days the condition improved. The drug is convenient to take - only 1 capsule per day.
Anatoly, 38, Moscow:
Took the Urorek a month. The drug helped, but reduced the severity of sensations in intimate proximity, the amount of sperm significantly decreased. However, the most unpleasant thing is the constant stuffiness of the nose.
Andrei Egorovich, urologist, Moscow:
It is impossible to completely cure chronic hyperplasia of the prostate. However, Urerek allows to normalize the condition of patients: reduce the frequency of urge to urinate, eliminate pain syndrome, achieve complete emptying of the bladder.
Price in Moscow
The cost of the drug at 8 mg in Moscow pharmacies varies from 590 to 650 rubles per packing number 30.The price of the drug, which is produced by 4 mg, is 615 - 660 rubles for 30 capsules.
Analogs
Silodosin analogs have a similar effect. Therefore, in the absence of medication, the appointment of:
- Alfuzosin;
- Hyperprost;
- Tamsulosin;
- Omnik of Okas;
- Dalf phase;
- of Omsulosin;
- Proflosin;
- of Tulosin.
Which is better, Urerek or Omnik?
Both drugs are classified as selective blockers for α1-adrenergic receptors, so they normalize urination.
Synonyms for
No synonyms are produced.
Terms of dispensing from pharmacies
For purchase, you need a prescription for a doctor.
Storage conditions and shelf life
Should be used within 24 months of production. Keep the medicine in a dark place, the temperature regime - no more than 25 degrees.