Chance to recover after pancreatic necrosis is large enough, but a favorable prognosis depends on the patient's age, the number of complications, the severity of the disease, the extent of the lesion, the intensity of the treatment, the concomitant diseases and the start of treatment. On average, the death from this disease comes from 40% to 70% of all cases, and most often this is due to the belated address to the doctor, extensive necrosis, the number of complications( more than three) and infection of the gland.
If necrosis touches most of the pancreas, then this condition of the patient can lead to death. If the patient survives, he has a chance to get a disability or he will be contra-indicated the following working conditions:
- labor, including high psycho-emotional stress;
- physical work of moderate severity;
- physical work of severe severity;
- work that requires a power failure;
- work requiring refusal to comply with the diet;
- work with hepatotropic and pancreatotropic poisons
All of the above activities are prohibited, since work under such conditions can lead to a repeated relapse of pancreatic necrosis with a less favorable prognosis, and more often with fatal outcome.
Sometimes cases of pancreatic necrosis are so serious that they do not leave a single chance for a full recovery and the most optimistic forecast for the patient will be disability.
The prognosis of getting a disability or temporary disability can be in a situation where the result of surgical treatment is the formation of abscesses in the abdominal cavity, external fistulas, deep vein thrombosis that caused impaired pelvic organs and strictures of the hepatobiliary zone.
In these cases, to determine the complications of pancreatic necrosis, the patient is referred to the ITU.There, the patient undergoes general tests, examines the enzymatic activity of the pancreas, the coprogram, and the sugar curve with the load. Then the person is sent to the ultrasound and computer tomography. In the case of stricture of the hepatobiliary zone, percutaneous transhepatic cholangiography, RCPH.
It is possible to predict what disability group can be obtained after treatment of pancreatonecrosis, based on the complications you have received. So, if your life is limited only moderately and you have had conservative therapy or surgery that did not have negative consequences, you have a chance to get a III group. If you have persistent external fistulas and a disorder of the digestive system of moderate severity, you can qualify for group II.
The chance of getting a group I disability after a pancreatonecrosis has patients with serious complications that can lead to an imminent death.
Mortality in pancreatic necrosis
The overall mortality rate for pancreatic necrosis nowadays is quite high - in 20-50% of cases the doctors state that the patient with this disease has died. This is especially true of destructive forms of the disease - the mortality rate is very high and, more often than not, is not characterized by positive dynamics of decline. Therefore, it is the increase in the destructive form of pancreatic necrosis that kills thousands of people each year, both men and women.
A number of proinflammatory cytokines, acting as mediators of the inflammatory process, damage the aggregate of organs and tissues. In most cases, the disease progresses quite rapidly and, accompanied by total organ damage, leads to rapid death. Significant progression from a local disease to a system of irreversible systemic consequences explains the high degree of lethality. But still, everything is not as scary as it may seem: a lamentable result arises only if the patient at the time does not seek advice from a qualified specialist who would prescribe a timely treatment based on the latest innovative techniques.
Causes of death in pancreatic necrosis
As confirmed by numerous studies, one of the main causes of death in pancreatic necrotic pancreatic necrosis are early toxemic and late septic manifestations of pancreonecrosis, accompanied by multiple organ failure, which occurs in every fourth case.
If the patient died at a later date, the cause of death is usually an infectious-toxic shock caused by complications, which is why an infection is considered an unfavorable factor in the development of the disease, greatly increasing the likelihood of a fatal outcome. The key factors that adversely affect the development of the disease are alcoholism and malnutrition, chronic stressful situations and cholelithiasis.
Thus, an adverse outcome is likely in cases where:
- changes the structure of pancreatic cells and tissues;
- forms necrotic foci;
- reactive changes occur in the foci of necrosis of the organ.
In case of occurrence of the above-described cases, the lethal outcome occurs from several hours to several days. Very rarely a patient can live a couple of weeks.