Antipyretic agents on the market are represented in a wide variety. Some medicines only lower the temperature. There are also medicines of complex influence. All variants refer to nonhormonal species.
Antipyretic: the principle of action of
The increase in body temperature causes special biologically active components that are formed under the influence of toxins, irritants and infectious agents. Pyrogens irritate areas of the hypothalamus, which leads to an increase in body temperature due to the limitation of heat transfer processes. This leads to a narrowing of the blood vessels, a decrease in blood supply to the blood vessels.
Antipyretic drugs act on the receptors of the hypothalamus, so their sensitivity to pyrogens decreases. At the same time, heat production by the body decreases, the heat transfer is improved due to the expansion of the blood vessels. Thanks to this mechanism, the body temperature returns to normal.
Doctors do not recommend using antipyretic agents to prevent fever. The main indications are:
- In adults, the temperature increase is more than 39 degrees.
- Body aches, fever and severe headache.
- In the presence of epilepsy, when the temperature is above 38 degrees.
Some drugs allow you to cope with muscle and toothache of an average nature.
The principle of action of antipyretics:
Rating of effective tools for adults
Some of the most popular are:
The main active ingredient in them is paracetamol. Because of additional substances, paracetamol starts to act faster, but because of them it is not recommended to take drugs for children under 12 years old.
Ibuklin, which contains paracetamol in combination with ibuprofen, is also classified as combined. According to reviews, the effect of the drug is rapid. One tablet can be used three times a day, but it is contraindicated in diseases of the gastrointestinal tract and chronic alcoholism.
With one of the most popular is Coldrex. It is available in effervescent tablets and in powder form. In addition to paracetamol contains ascorbic and phenylephrine. Tablets also have caffeine and terpinhydrate. According to reviews, Coldrex reduces body temperature, helps to cope with other symptoms of colds and flu.
Teraflu - a symptomatic drug, which by composition of the trip to the previous one. Available only in powder form. Contra-indications include children's age, diabetes, glaucoma and some other diseases.
Ibuprofen is one of the most effective antipyretic agents. He not only takes off the temperature, but also has an anesthetic effect. Simultaneous food intake slows the rate of absorption. Possible to take any infectious or colds. According to reviews, adults can alternate ibuprofen with paracetamol. This method allows you to bring down the temperature when other drugs do not fit.
One of the most favorite drugs is Aspirin. Children under 12 years old are not allowed to take it because of the possibility of toxic damage to the liver and brain. But adults are recommended to drink it not only from high temperature, but also to prevent blood clots, and also to protect the cardiovascular system.
Acetylsalicylic acid is not used in proven influenza because it increases the likelihood of bleeding due to increased vascular permeability. According to reviews, aspirin takes good temperature, but sometimes it is ineffective. Many people refuse to take it because of a large number of adverse reactions.
Adults often prefer Paracetamol. Tablets are manufactured by many manufacturers, so the price for them can be different. Paracetamol is in candles, suspensions, tablets and other forms. Allowed to take up to four times a day. The effect is observed after about 30 minutes and lasts up to 4-6 hours.
Adults often adjust metamizole to normalize body temperature. Preparations with this main active ingredient:
The therapeutic effect is achieved if you drink 250-300 mg three times a day. These drugs are on reviews at a lower step, because they are better able to cope with the pain, but as an antipyretic is not always helpful.
Nimesulide is another medicine with a pronounced antipyretic effect. It helps when other drugs are ineffective. Children are contraindicated, because of the negative effect on the liver. Adults should drink no more than 400 mg per day.
Another category of drugs, which according to reviews has good antipyretic properties - combined drugs. Usually they are designated as a remedy for colds and ARVI and have also an antiviral, analgesic or anti-inflammatory effect. The composition contains paracetamol in a different dosage, supplemented with aspirin or other active ingredients.
Inexpensive facilities for temperature
Antipyretics are usually given after 4 hours. Combined drugs have a prolonged effect, so they last for 5-6 hours. Drink them preferably at a temperature of not less than 38.5 degrees.the exception is the presence of concomitant diseases.
Antipyretics are used for the shortest course. In the case of long-term treatment, peripheral blood and liver and kidney conditions are monitored. If it is necessary to detect 17-ketosteroids, the drug is canceled 48 hours before the test.
Aspirin is contraindicated for people suffering from a sugar product. This drug reduces the level of sugar in the blood, so uncontrolled reception is prohibited. The remaining drugs are allowed for use, but only after consulting a doctor. For older people, the drug is selected taking into account the specificity of concomitant diseases.
Reviews of doctors about antipyretics:
What drugs can be pregnant and nursing
High temperature adversely affects the development of the fetus, so a decrease in temperature should occur necessarily. Paracetamol in large doses negatively affects the kidneys and liver. Therefore, in women who have diseases of these organs, the probability of developing side effects is quite large.
However, this active component does not adversely affect the fetus. Do not take any other medicines, including those based on ibuprofen. They can lead to fetal pathology.
When lactated Paracetamol is taken after breastfeeding. This will reduce the amount of the drug in the blood. It is best to use candles. They are considered less harmful, since the active components do not penetrate into breast milk.
Many herbs have antipyretic effect. These include:
- lime blossom,
Fried onions have the same properties. It is recommended to use it at the very beginning of the disease. Onions will not only relieve fever, but also prevent the development of the disease.
Popular antipyretic agents:
Among alternative methods, rubbing and compresses are considered effective. For the first often used apple bite or ordinary vinegar, diluted in water. Concentration should be so weak that it is possible without any consequences for your body to try such water.
Vinegar can also be used for compresses. The water of room temperature mixes with table vinegar in a proportion of 2: 1.Then:
- Wet a hygroscopic piece of cloth.
- Place on the forehead and on the forehead.
- For the relief of the condition, the compress is done for at least 40-45 minutes.
You can make and vodka compress. However, if the patient feels uncomfortable, then first put the bandage on the forehead, then on the calves and the wrist area. Do not forget to cover the patient after this.
How to bring down the temperature without tablets?
You can use several methods:
- Observe bed rest.
- Keep the room temperature up to 20 degrees.
- Wear things that absorb sweat well.
- Cool the skin by wiping it with a damp cloth.
Lemon juice, ginger, mint leaves and grape juice will help. A drink of these ingredients will help to remove the temperature.
What should I do if medications do not help?
There are many tools that allow you to knock down the temperature. If antipyretic tablets were ineffective, then you can combine their reception with alternative methods of exposure.
If this does not help, call a doctor or an ambulance. The paramedic will put a febrifuge. From injections, the effect usually comes faster. Urgently called a doctor if the heat is accompanied with pale or cyanotic skin.