Laticort - ointment, which includes hydrocortisone butyrate. The drug is effective in non-infectious skin diseases, accompanied by keratinization of the skin, itching and flaking.
Skin diseases are extremely diverse and diverse, and a variety of treatments are used to treat them. Quite a lot of such ailments are caused by an allergic reaction, the latter being caused both by the action of an external factor - household chemicals, for example, and by disturbances in the functioning of the body's immune system.
Laticort - ointment, which includes a glucocorticoid, which makes the drug an excellent assistant for the treatment of dermatitis, red lichen, psoriasis and other.
Features of the drug
Glucocorticoids are steroid hormones produced by the adrenal cortex. The most active of them is cortisol. It is extremely difficult to overestimate their significance. Under stress or shock, the level of substances in the blood rises sharply - this is one of the most powerful adaptation mechanisms to limit severe blood loss, eliminate the consequences of trauma and so on.
However, hormones constantly act in other, not so difficult circumstances. Thus, cortisol prevents the development of compounds that cause inflammation and allergic reactions. With a lack of a hormone, allergic reactions manifest themselves much more. But the local effect of the substance, even from the outside, suppresses this reaction.
Hydrocortisone butyrate - the active substance of laticort is just a synthetic analog of cortisol. As part of the ointment, it has an anti-inflammatory and anti-allergenic effect. Especially effective is the ointment in cases where the skin disease leads to her keratinization and loss of sensitivity. In this case, there is a strong seal in the epidermis. And hydrocortisone, unlike many other substances, is able to accumulate in the upper layer of the skin and lasts for a long time.
Laticort - Laticort, available in several dosage forms. It is intended for external use. The medicine is dispensed without a prescription, however it is necessary to inform the doctor about its use. A number of physiological procedures are not compatible with the use of hormonal creams.
Laticort( photo)
Dosage forms
The drug is available in 3 forms. All of them are intended for outdoor use.
- LACTICO CREAM 0.1% - is a homogeneous white mass, contained in aluminum tubes weighing 15 g. The cream is sold in a cardboard box with instructions.
- Ointment 0,1% - differs in consistency. This is a colorless fatty mass in aluminum tubes of 15 g.
- Lotion 0,1% is a colorless liquid, transparent, odorless. Lotion is sold in polyethylene bottles with a dispenser. The volume of the bottle is 20 ml.
Composition Latticorta
Hydrocortisone butyrate is the active substance of the ointment. The dose is the same for all forms of release. The amount and nature of the auxiliary substances is different.
The composition of 1 g of cream includes:
- hydrocortisone butyrate - 1 mg;
- excipients: liquid paraffin - 60 mg, cetostearyl alcohol - 72 mg, white petrolatum - 150 mg, cetomarogol - 18 mg, citric acid - 4.1 mg, sodium citrate - 2.8 mg, methyl parahydroxybenzoate - 2 mg, water -is added up to 1000 mg.
The composition of the ointment is somewhat simpler:
- active substance - 1 mg;
- excipients - white petrolatum up to 1000 mg.
Lotion composition:
- hydrocortisone butyrate 1 mg;
- additional components: glycerol - 30 mg, isopropyl alcohol - 0.5 mg, povidone - 2.5 mg, citric acid - 1.72 mg, sodium citrate - 0.78 mg, water - up to 1 ml.
Price
The cost of the ointment is traditionally lower than the lotion, as the latter thanks to the dispenser is more convenient to apply.
- The packaging price of the latricort ointment ranges from 136 to 212 rubles.depending on the manufacturer.
- The cost of the cream ranges from 130 to 146 r.
- Lotion costs from 172 to 237 rubles.for the bottle.
Pharmacological action of
Laticort has antipruritic, anti-allergic and anti-inflammatory action. First of all, this effect is due to a decrease in the permeability of capillaries.
Farmakodinamika
The manifestation of an allergic reaction is associated with a high concentration of lymphocytes and leukocytes in the lesion - both in the present and in the false if the immune system fails. Glucocorticoids, including hydrocortisone, prevent the migration of leukocytes and lymphocytes, thereby reducing inflammation. In addition, the substance blocks phospholipase, which reduces the production of leukotrienes.
Another useful feature is the quality of hydrocortisone - blocking the synthesis of fibroblasts and connective tissue in the inflamed area. This reduces the keratinization of the skin, the formation of seals and a decrease in sensitivity. This is due to the use of laticorta with psoriasis and red lichen.
The drug reduces flushing, that is, the blood overflow of small blood vessels, which leads to the defeat and irritation of the skin. This reduces itching, soreness, hypersensitivity to the skin.
Pharmacokinetics
The laticort after application is absorbed into the epidermis. The substance has the ability to accumulate in the stratum corneum, which provides a long duration of exposure and a low therapeutic concentration.
- In the blood, the drug is absorbed insignificantly - in children to a greater extent than in adults. Typically, this is due to a very large area of application or with the use of an occlusive dressing - airtight, from airtight material for 2-8 hours. In this case, hydrocortisone can have systemic effects.
- Metabolized substance in the epidermis. Its absorbed part is processed in the liver to butyric acid and excreted in urine and bile.
Indications
Laticort is used for non-infectious skin diseases characterized by keratinization, but with sufficient sensitivity to the drugs of the glucocorticoid series. Such ailments include:
- dermatitis as atopic - hereditary, and seborrheic - associated with abnormalities in the work of the sebaceous glands;
- contact eczema - rashes and itching of a neuro-allergic origin;
- red lichen is a chronic inflammatory disease characterized by itching, painful rashes on the skin and mucous membranes;
- psoriasis is an autoimmune disease;
- erythroderma is a number of pathologies that are characterized by rashes and itching on a large area of the skin;
- insect bites - in cases where they cause an excessive allergic reaction.
Laticort also is used for dermographism.
Instruction for use
Latsicort is used only externally. It is allowed to use both in small areas and with a large area of damage.
Adult
The way of application is simple: a cream or ointment is applied very thinly to the damaged area by massaging movements. The procedure is repeated 1-3 times a day for 1-3 weeks until a positive effect is obtained. It is important that the total amount of the drug used per day does not exceed more than 2 g in terms of hydrocortisone.
Carefully apply a laticort on your face, as it gets very irritating when you get into eyes or on mucous membranes. In addition, some of the side effects of the drug - perioral dermatitis, skin atrophy, aesthetically very unsightly and cause severe psychological discomfort.
It is possible to use occlusive dressings, especially with psoriasis. The bandage should be kept for at least 2 hours, but the best effect is provided with a longer hold - overnight.
If, within a week, the latticot is not affected or if the condition worsens, it is necessary to stop receiving and consult a doctor. Especially careful should be the elderly with a tendency to atrophy of the skin and subcutaneous tissue.
For Babies and Newborns
Use lathicort for the treatment of children allowed from 6 months. Apply the cream can be no more than 1 time per day. For facial skin, use is prohibited. The course is short-term and does not exceed 1 week.
In pregnancy and lactation,
Acquired hydrocortisone penetrates the placental barrier, and can lead to a slowed development of the fetus. However, according to vital indications, external use is allowed. In this case, the laticort is used locally, only in small areas and not longer than a week. With a large area of damage, hormonal ointments are prohibited.
Data on the ingestion of hydrocortisone in breast milk when it is not used externally. However, it will be used only in small areas and for a short period of time - not more than a week. It is strictly forbidden to apply ointment to the skin of the breast during feeding.
Contraindications
The use of ointment and lotion has its limitations:
- it is impossible to use the drug in case of allergic reaction to any components of the cream or in the presence of registered adverse reactions observed with stria, skin atrophy, pigmentation change;
- is prohibited from using laticort in infectious diseases, including bacterial infections - viral infections, chickenpox, cutaneous manifestations of syphilis, warts, herpes and the like;
- is also not tolerated for ulcerative skin lesions;
- it is forbidden to apply latticorta to the skin of the eyelids or around the eyes, especially with glaucoma and cataract;
- is not recommended for the use of ointments for skin atrophy, perioral dermatitis, ichthyosis, and simple acne;
- it is forbidden to use the drug when treating children less than 6 months and is not recommended - up to 2 years;
- with psoriasis cream treatment is conducted under supervision. There is a risk of addiction, which leads to relapse and an increase in the toxic effect of corticosteroids.
In diabetes, ointment should also be used very carefully. There is no direct contraindication here, but the response to hormonal drugs in systemic diseases is not always accurately predictable.
Side effects of
Side effects in the treatment of laticort are extremely rare, usually a local reaction - irritation, contact dermatitis. With prolonged use or after using an occlusive dressing, striae, sweating, discoloration of the skin, folliculitis may occur.
As a rule, all side effects are reversible, and disappear after the course.
Special instructions
- Hormonal ointments, including laticort, can not be used more than 2, maximum 3 weeks. With prolonged use, the risk of side effects increases significantly.
- The use of the drug on the face skin and in the groin area is limited, since there is a high risk of side effects even at the shortest possible time.
- If during the treatment in the area where the ointment is used, an infection has appeared, the drug should be discarded.
- The drug is not overdosed. Theoretically, it can lead to the appearance of signs of hypercorticism.
- The use of ointment does not affect the mental state or coordination ability, so there are no restrictions on driving or equipment management.
- No information on any latticort interaction with other drugs has been recorded.
Reviews
Laticort is a fairly popular drug used to treat various forms of dermatitis and eczema. The course of treatment is not so long that there are side effects, and the skin acts very well on the skin.
As a rule, patients express many fears when using hormonal ointments, especially when treating children. In most cases, they are groundless, since the absorption of the drug into the blood with external use is very low and can cause complications only if there are quite certain diseases.
The drug is dispensed in pharmacies without a prescription. However, using it yourself without doctor's appointment would be extremely unreasonable.
Analogs
Hydrocortisone is part of the following drugs, which can be considered analogous to laticort:
- hydrocort;
- ;
- corteid;
- is a lokoid;
- hydrocortisone ointment.
Sometimes, instead of this drug, use Afloderm. Laticort - ointment, which includes hydrocortisol. This substance is very effective in treating a variety of dermatitis and cutaneous eczema, accompanied by keratinization of the upper layer of the skin.