For some people, combating acne is turning into an agonizing marathon for years. The skin, cleansed for a while, again becomes inflamed and covered with hated acne. Do not despair and engage in self-medication. The doctor will tell you the right remedy called Roaccutane. An effective drug has contraindications. To appoint him, a specialist should check whether he is suitable for a particular patient.
Features of the preparation
Roaccutane, due to the main active substance called isotretinoin, inhibits the development of the stratum corneum of the epidermis and inhibits the multiplication of pathogenic bacteria.
Roaccutane( photo "before" and "after")
Roaccutane is available in capsules, which are sometimes mistakenly called tablets. There are no other medicinal forms of the drug.
- Red-brown capsules have an oval shape. The internal contents, which is a suspension of yellow color, are not visible. Each capsule has a black inscription ROA 10.
- Capsules may contain 10 or 20 mg of active ingredient. Roaccutane is sold in cardboard packs of 3 blisters( 30 capsules in a pack) and 10 blisters( 100 capsules in a pack).
In this video the girl will tell about her treatment with Roaccutane:
|Composition of suspension||Composition of capsule shell||Composition of ink on the shell|
| The main active ingredient is isotretinoin. |
Additional components: soya bean oil, hydrogenated, as well as partially hydrogenated soybean oil, yellow beeswax.
|Glycerol, gelatin, hydrolyzed potato starch, sorbitol, mannitol, titanium dioxide, dye E172.||Shellac in combination with the E172 dye or finished special black ink.|
Roaccutane is not considered a cheap medicine. In pharmacies and online pharmacies it can be purchased within:
- 10 mg №30 - from 1700 to 2300 rub
- 20 mg №30 - from 2800 to 3500 rub
- 10 mg №100 - from 4000 rub
- 20 mg №100 - from10000 rub
The cost of the drug depends on the country of manufacture, the amount of active ingredient and the number of capsules in the package, the price policy of a particular pharmacy network.
The drug has anti-inflammatory and anti-seborrheic effects on the skin.
Isotretinoin, the main active component of Roaccutane, is a biologically active form of vitamin A. It has the following effects on the skin:
- reducing the stratum corneum, rapidly penetrating the affected epidermal zone
- inhibits the formation of sebum, reducing the size of the sebaceous glands themselves
- suppresses the multiplication of pathogenic bacteria
The concentration of active substance in the blood can be calculated from the data obtaineds after the first dose. It increases if the drug is taken with food. This indicator will be 2 times higher than when taking capsules on an empty stomach.
The percentage of drug withdrawal from the body using bile and kidney is approximately the same. Two weeks after the end of the course of therapy, the drug is excreted completely from the body.
The doctor in the video below will tell you how to properly take this medication:
Roaccutane is prescribed if one of the skin diseases is diagnosed:
- Acne( acne vulgaris) with the formation of pustules, pigment spots, scars and pathological hemorrhages
- Acne rosacea
- Purulent hydrangea
- Violation of coronary processes( follicular keratosis, keratodermia of the soles and palms, ichthyosis, red hair pityriasis)
Instruction for use
Pharmacythe drug is completed with instructions for use. Self-medication can only hurt. Scheme and duration of therapy is determined by the attending physician.
Before and after taking
Capsules are taken orally together with food 1 to 2 times a day. The regimen is started with 0.5 mg / kg per day. The duration of the first stage of therapy is from 2 weeks to 1 month. At the next stage the dose of the drug is increased to 1 mg / kg and lasts from 3 to 5 months.
The physician corrects the treatment regimen according to the therapeutic effect, adverse reactions, drug tolerability of the patient. Tangible results of treatment are usually observed after 1 - 2 months of taking the drug. Sometimes a pronounced therapeutic effect can occur only after 4 to 5 months. If during this time the amount of skin rashes decreased by more than 70%, the medication is stopped.
- In the case of a relapse, the doctor appoints a break in treatment for 2 months. If against the background of taking the drug there is an exacerbation of the disease, then the daily dose is reduced by two weeks to 0.5 mg / kg.
- For the treatment of rosacea, purulent hydrodenitis, folliculitis, Roaccutan therapy is prescribed for 4 months at a rate of 0.5-1 mg / kg per day.
- For violations of keratinization, the treatment with Roaccutane capsules lasts at least 4 months with a daily dose of 4 mg / kg. The dose is reduced if there is an improvement in the patient's condition.
For children and newborns
For children under 12, the drug is strictly contraindicated.
In pregnancy and lactation
- Roaccutane is absolutely contraindicated in pregnant women and mothers breastfeeding, since there is a serious risk of developing pathologies in the child.
- Women of childbearing age need to take care of reliable methods of contraception when taking medication.
Application for hair growth
Against the background of treatment with the drug, there may be increased hair loss. Such a reaction is caused by the narrowing of the vessels of the scalp under the influence of the drug, which leads to a lack of nutrition of the hair. This unpleasant effect persists for some time after the end of therapy.
It is not necessary to combine the administration of Roaccutane capsules with hair masks, since most of them contain a high dose of vitamin A, which is prohibited for simultaneous use with this drug. Hair growth will recover after a short time after Roaccutan's treatment is completed.
The drug has a number of serious contraindications for use:
- hypervitaminosis A
- individual intolerance to drug components
- liver function disorder
- highly elevated blood lipid level
- concurrent treatment with drugs from the tetracycline group
- children under 12 years of age
- pregnancy planning period
With caution, the drug should be used if there are problems such as:
- alcohol dependence
- lipid metabolism disorder
Side effects of
When receiving roacutane, unwanted reactions from various organs and body systems can occur:
|Organs and body systems||Side effects|
|CNS||Depression, changes in behavior, increased intracranial pressure, headaches, convulsive seizures, visual impairment.|
|Sensory organs||Photophobia, optic nerve edema, impaired color perception, eye irritation, cataract, conjunctivitis, hearing impairment.|
|Digestive system||Vomiting, nausea, diarrhea, colitis, pancreatitis, bleeding.|
|Hemostatic system||Leukopenia, anemia, neutropenia.|
|Respiratory system||Patients with bronchial asthma may have bronchospasm.|
|Musculoskeletal system||Articular and muscular pain, arthritis, hyperostosis, calcification of tendons and ligaments.|
|Skin covers||Itching, rash, sweating, thinning and hair loss, hyperpigmentation, increased skin trauma, infection.|
|Effects of hypervitaminosis A||Nasal bleeding, dry skin, hoarseness, conjunctivitis, temporary lens intolerance.|
|Immune system||Increased risk of infectious diseases caused by gram-positive pathogens.|
|Laboratory indicators||Increase in the number of cholesterol and triglycerides, a decrease in the blood of HDL.|
|Other reactions||Allergic vasculitis, hematuria, lymphadenopathy.|
Most often, adverse reactions are reversible, but some of them may persist for a long time after the end of treatment.
- Donors are prohibited from donating blood during Roaccutane administration.
- It is recommended to avoid contact lens wear during therapy.
- Patients with diabetes mellitus need to establish a constant control of blood sugar levels during treatment with Roaccutane.
- Women of reproductive age should carefully avoid conception during the period of drug therapy.
- The entire period of therapy should be avoided by exposure to ultraviolet light.
- If the appearance of side effects, the drug is canceled.
- When taking medication, it is not recommended to sit behind the wheel and operate complex mechanisms.
Interaction with other drugs and alcohol
- Preparations from the group of tetracyclines weaken the action of Roaccutane and increase intracranial pressure.
- The risk of sunburns increases with concurrent administration of Roaccutane with drugs that increase skin photosensitivity, for example, with sulfonamines and thiazide diuretics.
- Hypervitaminosis A develops when taken concomitantly with retinoids.
- Simultaneous administration of the drug and alcohol can lead to serious side effects.
Doctors and patients note the high efficacy of the drug while observing the treatment regimen. During the treatment, liver monitoring is mandatory.
- Retinoic Ointment
Feedback on Roaakutane given in this video: