Oflokainovuyu ointment is used to treat skin pustular rashes, open wounds, burns. Produced by the pharmaceutical company Darnitsa( Ukraine), the trade name - Oflocain( Oflocain).Oflokainovaja ointment( Oflokain), its instruction on application, the price in Russia, responses and analogues will be considered by us in this article.
Features of the drug
Medication Oflokain-Darnitsa is a thick, homogeneous mass of white with a characteristic odor.
Composition of oflokaine ointment
Ophthalmic ointment includes:
- fluoroquinolone antibiotic ofloxacin - in 1 g of the drug - 1 mg ofloxacin;
- local anesthetic lidocaine - 1 g of the drug includes 30 mg of lidocaine.
Medicinal forms
Ophthalmic ointment is a drug for external use. Produced in aluminum tubes of 15 g, 30 g, are packed in glass jars of 1 kg.
Tuba weighing 15 g costs 40 - 50 hryvnia in drugstores of Ukraine, Russia - 125 rubles.
Pharmacological action
The spectrum of activity of a multicomponent agent is determined by the combination of the activity of the main components - ofloxacin and lidocaine.
Pharmacodynamics
Due to the antibiotic ofloxacin, the ointment has an antimicrobial effect. The hydrophilic base allows the preparation to quickly absorb, penetrate into the deep layers of the skin, distributing the medication evenly over the entire thickness of the skin on the affected area.
The action of ofloxacin is based on the suppression of DNA replication of Gram-positive and Gram-negative bacteria. Antimicrobial activity of the antibiotic extends to asporogenous, anaerobic, hospital bacterial strains that are resistant to many other types of antibacterial agents.
Lidocaine anesthetizes, eliminates partial swelling and inflammation, dries the wound. The analgesic effect of lidocaine is based on its ability to block the sodium channels of cell membranes, to prevent the conduction of a nerve signal.
Pharmacokinetics
Skin prevents the penetration of the components of the drug into the total blood flow, provided that the integrity of the skin is preserved. If the drug is applied to an open wound, up to 3% of the mass of the applied drug penetrates the systemic bloodstream.
In the blood, the highest concentration of the components of the drug is detected 3-4 hours after use. After 6 hours after applying the ointment to the skin, the presence of the drug in the blood is not determined.
Indications
Ointment with antibiotic Oflokain-Darnitsa is used to treat complicated infected wounds at the 1st stage of the wound process:
- pustular skin rashes;
- purulent burn wounds, including with chemical burns;
- infected skin wounds;
- injuries as a prevention of suppuration;
- postoperative complications;
- in the postoperative period after removal of limbs for stump treatment;
- trophic ulcers;
- facial phlegmon;
- decubitus.
Has found offokain-ointment the application and in gynecology.
On how to use ophthalmic ophthalmic for the treatment of adults and children, we will discuss below.
Instructions for use
Oflokainovuyu ointment used:
- for the treatment of the affected area of the skin;
- dressing application;
- tamponation of cavities filled with pus;
- administration of turunda with ointment in the fistulous passageways.
After preliminary treatment of the wound with a solution of antiseptic and drying on the wound, a thin layer of ophthalmic ointment is applied and then covered with a sterile bandage.
The number of applications per day depends on the presence of pus in the wound. The purulent wound is treated once a day. With a large amount of pus in the wound, bandages are changed 2-3 times a day. It is enough to treat a clean wound once a day. The duration of treatment is 7-14 days.
Ophthalmic ointment is used to treat gauze tampons, which are placed in a cavity filled with pus, formed after surgical removal of the tumor, part of the body, the skin area.
Contraindications
- The drug is prohibited in pregnancy, lactation, is not allowed for use to children, is contraindicated in phase 2 of the wound process.
- Ophthalmic ointment is not prescribed for hypersensitivity to the active and auxiliary components of the drug.
Side effects of
Ointment is well tolerated. There may be a burning sensation that quickly passes, irritation, redness of the skin, hives. In rare cases, an allergy, Quincke's edema is possible.
Special instructions
- No information about drug overdose.
- The use of ointment does not affect the ability to drive vehicles.
- Wound surface before application of the product is treated with a disinfectant.
Interaction with drugs
The drug remains effective in external use in the presence of pus, blood, when using other medicines. Monoamine oxidase inhibitors increase the analgesic effect of lidocaine.
The drug is undesirable to apply:
- concomitantly with other topical preparations;
- with antiarrhythmic drugs because of the risk of systemic action.
Reviews
- Consumers respond to the drug positively. The effectiveness of the drug in the treatment of purulent furuncles is noted, and ointment for burns is especially helpful. It not only eliminates inflammation, but also anesthetizes.
- Ointment is characterized by the property of hyperosmolarity, it as it draws a purulent exudate from the wound, which makes it especially effective in the first phase of injury.
- About Oflokainovoj ointments positively respond not only patients, but also the doctors widely using a medicinal product in surgical practice.
Analogues
Analogues of Oflokainovoy ointment - Russian drug Oflomelid, Ukrainian drug Dioxysol-Darnitsa. The antibiotic fluoroquinolone series is contained in the preparation of Floxal, a similar effect is possessed by the ointments Levosin, Levomecol, Iruksol.