Modern means, which make it possible to improve the skin condition in a short time with various dermatological lesions, made it possible to relieve the main symptomatology even with such a formidable disease as psoriasis. And among the analogs, it is worth mentioning separately the preparation Acitretin, which, thanks to its balanced composition and the minimum number of adverse events, allows to improve the condition even in neglected conditions.
Being an effective tool for solving many dermatological issues, Acitretin can be used in both monotherapy and in complex therapy. At the same time, its effectiveness increases when used together with drugs that have a similar therapeutic effect. According to medical statistics, it is Acitretin that allows the most rapid regeneration of the skin, eliminating the concomitant inflammation. And this article will review the instructions for the use of Acitretin, its price, analogues and reviews of specialists.
Features of the preparation
The most important characteristics of the drug under consideration include its ability to quickly stop the current pathological process, restoring the epithelial layer of the skin, reducing the level of soreness. Peeling, which often accompanies the skin lesion process, also decreases with the use of Acitretin.
In this case, the drug has almost no side effects - it allows you to apply it in the complex treatment of skin lesions with increased sensitivity of the patient's body to the active substance Acitretinum. The agent does not cause teratogenic, carcinogenic effects both on the affected parts of the skin, and on its healthy parts.
Composition of Acitretinum
The composition of the drug is its maximum balance, which determines the high degree of effectiveness even in particularly neglected skin lesions. The activity of the active substance is determined by the complex effect of the accompanying components, which allow full manifestation of all the qualities of the drug.
The drug is available in the form of a powder, which has a yellowish tinge and easily dissolves in water. Due to the rapid penetration into the skin of the active substance, there is an accelerated process of regeneration of damaged tissues, elimination of the main sources of inflammation. The skin in a short time acquires its original healthy appearance, the symptoms of the current pathological process in it decreases.
Prices and forms of Acitretinum, used for psoriasis and other ailments, will be described below.
Dosage forms
In the sale the preparation is presented in the form of a powder, which dissolves in water and has a high degree of efficiency due to the activity of the constituent components. The powder is located in capsules with a rapidly dissolving surface that dissolve quickly under the influence of gastric juice and even saliva during the swallowing stage. Capsules are sold in a vial made of dark glass.
The bottle is located in a cardboard package, the number of capsules in one bottle is 30 pieces. Simplicity of reception provides an opportunity of its or his purpose or appointment even to children: the preparation dissolves in potable water and is used in the form of a solution up to meal. The dose of the drug and the duration of its use largely depend on the stage of the disease and the area of skin lesions.
The cost of the facility depends on the mark-up of the pharmacy in which the drug is sold. And the price can vary from 780 to 980 rubles per package.
Pharmacological action of
The activity of the active substance causes the possibility of obtaining pronounced results after a short time since the onset of Acitretin. Dissolution of the capsule begins already when they enter the oral cavity, and then in the esophagus.
With the penetration of the active substance into the epidermal cells, the process of their division slows down, which helps to eliminate the process of thickening the epidermis. It is this quality that can be considered the main one when prescribing the drug for various skin lesions.
Pharmacodynamics
The cleavage of the drug Acitretin for its components ensures its maximum effectiveness when taken. The highest concentration in the body reaches the drug after 1-2 hours from the time it was taken. At the same time, rapid excretion with the help of the kidneys ensures the absence of side effects: in a few months after the appointment of the drug as part of the treatment in the blood does not show even traces of its components.
Pharmacokinetics
The process of renewal of the cells of the upper layer of the epidermis in the appointment of the drug in question makes it possible to stimulate the body to combat the root cause of the disease. Even acute forms of psoriasis are susceptible to Acitretin, especially in the appointment of a comprehensive treatment.
The absence of adverse events during admission makes it possible to use the drug even for people with increased sensitivity to the components.
Indications
The drug Acitretin is commonly used in the treatment of a variety of skin lesions. In the best way he proved himself in the complex treatment approach by activating the properties of the active ingredient with drugs having a similar effect on the body.
To conditions in which the use of Acitretin is recommended, the following diseases and skin lesions should be attributed:
- of eczema of various nature;
- psoriasis of any stage of development, as well as ichthyosomorphic erythroderma of Broca and psoriatic erythroderma;
- Bowen's disease;
- red lichen, localized on the scalp;
- with pronounced disturbances in the processes of keratinization of the upper layer of the epidermis.
Also, the remedy is prescribed when follicular and other forms of dyskeratosis, congenital ichthyosis and other forms of skin damage are identified. Due to the absence of side effects, the remedy perfectly helps with other manifestations of dermatological diseases of varying degrees of intensity.
Instruction for use
The use of the drug depends on the diagnosis, because each disease requires an individual therapeutic regimen to obtain the greatest effect in treatment.
- With eczema of any nature, a drug intake of 2-3 capsules per day is usually prescribed. They are washed down with water, it is recommended to take them before meals. Duration of treatment is based on the results obtained and can usually be from 3 to 6 weeks. Next, you should take a short break( 1 week), then repeat the treatment until a stable result.
- For , the initial stages of psoriasis , the duration of treatment with Acitretin should be at least 4 weeks: during this time the process of keratinization of the upper layer of the epidermis begins to stabilize, the main symptoms of the disease disappear or become less noticeable.
- With advanced stages of psoriasis the drug intake should have a long duration: from 5 to 12 weeks.2-3 capsules a day are taken.
Contraindications
- Contraindications include all types of inflammatory processes in the body at the stage of exacerbation, in the presence of hypersensitivity to any component of the drug under consideration, with a tendency to allergies.
- Acitretin should also be used with caution in the elderly, during pregnancy.
- You should not prescribe a remedy for severe liver and kidney damage, with heart failure.
Side effects of
The following are side effects:
- thinning of the upper layer of the epidermis;
- peeling and hypersensitivity to the skin;
- inflammation of the treated skin areas;
- headache and dizziness.
There may also be muscle weakness, conjunctivitis, which have a mild manifestation.
Special instructions
- The period of breastfeeding requires increased accuracy when using Acitretin.
- Also under the supervision of a doctor, the remedy is used during pregnancy.
Interaction with other medications
- The use of acitretin in combination with drugs that are also derivatives of retinol( vitamin A) is not recommended due to an overdose of the active substance.
- Because the drug has no pronounced sedative effect, sedatives can be used concomitantly with its administration.
Reviews
According to the customers, the products of Acitretin are excellent for a variety of skin lesions. This allows you to expect a pronounced result in a short time from the time you start receiving. Many patients noted the absence of side effects in the treatment of the drug;his thoughtful composition guarantees the removal of the main symptoms of diseases associated with lesions of the skin.
Due to the susceptibility of the body to the active ingredient, the therapeutic effect of the drug Acitretin has an effect even in the case of neglected forms of psoriasis, when other drugs have no pronounced manifestation.
Analogues
The following medicines used in the treatment of skin lesions can be classified as drugs with similar effects:
- Beroxane;
- Psoberan;
- Oxassaren.
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