Migraine is one of those diseases that people usually do not treat with the proper seriousness, taking the usual painkillers. Sometimes this disease turns out to be so neglected that only triptans can help get rid of the throbbing pain. This group of drugs is produced on the basis of serotonin.
Form release
Triptans are available as a spray and tablets.
List of preparations containing tryptane
| Name of the drug | Active ingredient | Features |
| Zomig | Zolmitripan | The effect of the drug begins 20 minutes after ingestion. Excellent helps relieve pain during menstrual migraines. The drug can be used during feeding and pregnancy. It goes well with some other analgesics. |
| Sumatriptan | This category of drugs is the most studied. The action occurs within 15-30 minutes, and the fastest effect is achieved after using the spray. When receiving, other migraine preparations containing ergotamine should be excluded. |
| Relpax | Elethriptan | Has a minimum of side effects and high efficacy. The result will be visible after 30 minutes after ingestion. When taking antifungal medications and antibiotics, it is not recommended to take Relpax. Use during pregnancy is permissible. |
Principle of action of
The action of triptans is aimed at narrowing the dilated cerebral vessels.
The drug acts on the bases of the nucleus and receptors of the trigeminal nerve, which contributes to a decrease in sensitivity to pain.
They are also shown in cases when the disease recurs, since it has the property to reduce symptoms such as light and phobia, vomiting, nausea.
Clinical efficacy of
Efficacy is increased several fold if a migraine tablet was taken within the first 15 minutes after the onset of pain. According to studies, in more than 60 percent of cases, tryptans give a more tangible result, compared to other analgesics.
Features of the use of triptans
These medicines are used only after aura - violations in the visual, olfactory, auditory receptors.
In some cases, when the headache builds up gradually, tryptanes should not be taken at all, but replaced with another usual analgesic.
It is possible that the pain after taking the drug may return again. In the event that the pain is not pulsating and not intense, it is more appropriate to replace tryptane with another analgesic of a non-specific nature.
How to use
Tablets should be taken orally. The dosage of tryptane is 2.5 mg. In case the pain resumed, you can repeat the drug, but not earlier than 2 hours after taking the previous pill.
Spray is sprayed into the nasal cavity, which provides better absorption.
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Contraindications
The use of triptans is completely contraindicated in the presence of the following diseases:
- Hypertension;
- Arrhythmia;
- Ischemic disease;
- Angiospastic angina pectoris;
- Disturbance of cerebral circulation;
- High sensitivity to constituents of triptans;
- Adolescence.
With maximum caution, the drug should be used for lactation, pregnancy, as well as for severe hepatic or renal failure.
Side effects of
Muscular and osseous systems: myalgia, muscle and general weakness. Cardiovascular system: tachycardia, angina pectoris, heart palpitations, myocardial infarction.
Urinary system: polyuria, frequent urination. Nervous system: asthenia, dizziness, loss of sensation, sensation of heat, drowsiness.
Digestive system: dry mouth, intestinal infarction, abdominal pain, nausea, ischemic colitis. Possible allergic reactions: angioedema, hives, anaphylactic reactions.
Interaction with other drugs
When treating migraine with tryptanes, it is necessary to limit the intake of analgesics of other species.
Overdose of
Exceeding the daily allowance of this medication threatens the patient with the following consequences:
- Drowsiness;
- Nausea and vomiting;
- Seizures;
- Tachycardia;
- Decreased attention.
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Storage conditions
Store preparations and sprays belonging to the category of triptans, necessary in a room, the temperature in which does not exceed 30 degrees. Avoid direct sunlight. In case of observance of the described storage conditions, the shelf life of the triptans may be three years.
Price
The cost of triptans for migraine varies from 140 to 1500 rubles.
Conclusion
Undoubtedly, triptans are the most effective remedies for with migraines. However, it should be remembered that it is better to select drug data under the supervision of a physician.
In some cases, tryptanes can be ineffective, so it is advisable to consult a doctor who will help you choose the right drug.
Triptane intake during pregnancy and against the background of antibiotic therapy requires strict control of the attending physician. The appearance of signs characteristic of an overdose should be the reason for the complete withdrawal of the drug and a second visit to a specialist.