Otoze drops: instructions for use, analogues, doctor's reviews

Otofa - antibacterial ear drops. They are used only after consultation with a doctor.

Composition, form, package

ear drops otoph Drops contain 26 mg( 20 thousand IU) in one ml of rifamycin sodium. In one bottle it contains 260 mg( 200 thousand IU).As auxiliary substances macrogol, ascorbic acid, potassium metabisulphite and some other components are used.

The cardboard pack contains one bottle made of dark glass. It is supplemented with a dosage pipet. The liquid itself is a transparent red-orange color.


Drops are produced in France in the "BUSHARA-RECORDATE Laboratory".

Indications for use

Drops are used for various infectious lesions of the auditory canal. Effective for diseases caused by:

  • by staphylococci,
  • pneumococci,
  • gonorrhea,
  • by microbacteria of tuberculosis,
  • by proteins.

The drug acts on various strains of microorganisms that are not sensitive to other antibiotics. Therefore, can be used to treat:

  • inflammation in the outer and middle
  • organic lesions of the tympanic membrane,
  • purulent processes.


The main limitation is the increased sensitivity to rifamycin. Adequate safety studies of the drug during admission during pregnancy were not conducted. Therefore, pregnant women and women with breastfeeding drops are shown in extreme cases.

Mechanism of action

The therapeutic effect of drops is related to the specific binding of rifamycin to RNA polymerase bacteria. Due to this, the growth and multiplication of bacteria is suspended. In addition to antibacterial action, the drops have an anti-inflammatory effect, then with prolonged therapy, microbes may develop tolerance to the active components.

Rifimycin acts simultaneously in two ways. First, it has bactericidal action, and then blocks their multiplication. Therefore, most infections of the middle ear are effectively eliminated.

Instructions for Use

Adults are instilled with five drops three times a day. You can pour the drug in your ear for several minutes twice a day. Children are prescribed three drops three times a day. Duration of treatment is one week. Before using drops it is recommended to warm the bottle. To do this, you need to hold it in your hand. This will allow the solution to become the right temperature.

Form of preparation Otofa

of the formulations of the drug

Side effects of

Otofa can lead to reddening and irritation of the skin. Sometimes there are allergic manifestations. In this case, the drug should be discarded. When tympanii tympanic membrane can be painted in pink. This becomes visible only when examining the auditory meatus in the process of otoscopy .


Due to the fact that the drug is not practically absorbed and does not pass into the bloodstream, an overdose is unlikely.

Special instructions

It is not recommended to allow contact of the solution with clothing, since stains may remain on it. In addition, due to the rapid manifestation of drug-resistant strains, long-term use of otofa is not recommended.

Drug Interactions

No clinically significant drug interactions with other drugs have been identified.

Reviews about drops

Many people emphasize the ability to cure otitis using drops in a short time. Users note that it does not relieve soreness, so it can be used in conjunction with other anesthetics.

How to use the drug Otofa in our video:

Drops prices Otof

The cost of ear drops depends on the features of the pharmacy network. The smallest price is 180 rubles. In some online stores, you will have to pay about 600 rubles for medicine and delivery.


There are no analogues. However, the active substance rifamycin is contained in the solution for injection of Rifogal. A similar effect is provided by Ophthalin, Otinum, Otipax and some others.

Cheap analogs

Lower cost have nose drops Noxprey, Rinazolin, Sofredeks, Loprax. But these drugs have a completely different composition.

The photo shows analogs of ear drops of Otofa

Analogues of drops of Otof

Synonyms of medication

Anauran. These are also ear drops, which include lidocaine, neomycin, polymyxin B.

Conditions for dispensing from pharmacies

The drug is sold only on prescription.

Storage conditions and shelf life

The bottle can be stored in a dark place at a temperature of not more than 15 degrees. Shelf life is three years.

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