Diazolin is an antiallergic drug that is classified as an H1-histamine receptor blocker. Active active substance of the drug is mebhydrolyn. Many doctors note the high effectiveness of Diazolin, therefore it is widely used for the treatment of allergies and pathology of ENT organs in adults and children. It is worth considering in more detail the features of the use of the drug.
When the use of
is indicated The use of diazoline results in the blocking of H1-histamine receptors. They contribute to the development of an allergic reaction.
The drug does not cause a decrease in the level of histamine in the bloodstream, only prevents the interaction of the active substance with the corresponding receptors.
Diazolin is prescribed for the following pathologies:
- Allergy, which is caused by insect bites;
- Hay fever, eczema;
- Allergic reactions against the background of the use of various drugs;
- Vasomotor rhinitis;
- Food allergy;
- Sinusitis;
- Conjunctivitis. The drug reduces the severity of itching and other unpleasant symptoms;
- To prevent allergic reactions in patients who suffer from seasonal allergies;
- Rash of different genesis;
- Allergic otitis;
- Bronchial asthma. The results of the therapy are ambiguous: treatment with the drug in some patients causes a positive dynamics, in others - the improvement of the condition was not noted.
Dosage form of the release
The drug is produced in tablet form, in the form of pellets, which have a rounded shape. Tablets of white color, the mass of which is 10 mg, have a special risk and facet. Diazoline is available in 50 or 100 mg. Dragee or tablets are in a blister pack of 10 or in bottles of 20 units each.
Children's uniform with a reduced dosage is not released. For small patients, the drug is released in the form of soluble granules, which are bred in pure water or juice.
In the photo the dosage form of Diazolin
Scheme of application
According to the annotation Diazolin is used inside during food intake or after it. Tablets are drunk whole, squeezed with enough liquid. The action lasts for 2 days, but the indicator may vary depending on the history of the disease and the severity of the pathology.
Depending on the pathology, adults and children after 13 years of age should take between 50 and 300 mg of meghydroline per day. In this case, the dose can be divided into 2-3 doses. The maximum daily dosage is 600 mg, single dose is not more than 300 mg.
For the treatment of diseases in children, the following regimen is used:
- From the age of 13, an adult dose is used;
- In children 6 to 13 years of age, the dosage is 50 mg of mebhydroline no more than 3 times a day;
- Children under 6 years of age - Diazoline is prescribed 25 mg three times a day.
Features of the prescription of infant suspension for a child younger than 6 years:
- Up to 3 years, 2.5 ml of suspension is prescribed twice a day.
- The recommended dose of 3 to 6 years is 5 ml to 3 times a day.
In mild cases, it is sufficient to use a single dose of Diazoline, so that all unpleasant symptoms disappear. In severe pathologies, the course of the drug is prescribed for 5-10 days. In any case, the dose and duration of therapy should be determined by the attending physician.
For the treatment of sinusitis( inflammation of the maxillary sinus of the nose), frontitis( inflammatory process in the frontal sinus) or polysynusitis is widely prescribed diazolin. The drug has a strong anti-edematous effect, so it significantly alleviates the symptoms of the disease.
During pregnancy, the intake of Diazolin can be caused by malnutrition, seasonal allergies, colds, hormonal failures. The drug can not be prescribed on its own - the decision to take an antihistamine should only be taken by a doctor.
Usage Diazoline is shown only in the third trimester, because at an earlier time the drug can trigger the development of severe toxemia in the pregnant woman. Dosage should not exceed 300 mg during the day. In parallel with taking Diazolin, you need to adjust the diet, excluding citrus, caffeine, chicken, eggs, food additives, canned food.
Symptoms for which diazolin is prescribed
Interaction with other agents
Diazolin is able to enhance the effect of drugs that lead to CNS depression( hypnotics, barbiturates, sedatives).It is also better to refuse simultaneous reception with drugs that cause irritation of the mucosa of the gastrointestinal tract. The drug is not compatible with alcohol.
Possible side effects of
Usually the drug is well tolerated in patients of different age groups. However, there may be some unpleasant symptoms:
- Nausea;
- Heartburn;
- Pain in the epigastric region;
- Violations of urination;
- Dryness in the oral cavity;
- Development of agranulocytosis;
- Irritation of the gastric mucosa;
- Development of agranulocytopenia;
- Violations from the central nervous system: dizziness, impaired coordination, mild drowsiness, confusion;
- Allergic reaction.
Usually side effects occur when there is a violation of medical instructions and excess dosage of the drug, as well as in the presence of intolerance mebhydroline. The duration of unpleasant symptoms depends on many factors, but with a sharp deterioration in the state of health, it is necessary to cancel the drug.
In childhood, such side effects can occur:
- Panic attack;
- Sleep disorder;
- Increased excitability;
- Tremor;
- Mood swings.
Basic contraindications
Diazolin is classified as the first generation of antihistamines because it is not a highly selective medication. It is also capable of blocking H2 receptors that are located in the stomach, as well as H3-histamine receptors located in the vessels, organs of the central nervous system. That is why the drug has contraindications:
- Exacerbation of peptic ulcer;
- Pylorostenosis;
- Prostatic hyperplasia;
- Epilepsy;
- Closed-angle glaucoma;
- Heart rhythm disturbances;
- The onset of pregnancy, lactation;
- Age under 2 years.
Advantages of Diazoline
The drug has a pronounced anti-edematous effect and a mild analgesic effect, which is its main advantage. This quality makes it possible to widely use Diazoline in the treatment of diseases of ENT organs. The main area of action is edema of the mucous, triggered by allergic reactions.
Also to the positive characteristics of Diazolin is the absence of a pronounced hypnotic effect in comparison with other antihistamine drugs of the first generation.
The drug is quickly absorbed by the intestinal mucosa. The first effects from admission patients are noted within 15-20 minutes after oral administration.
Instructions for Diazolin can be viewed in our video:
Storage characteristics
Diazolin is classified as a drug of list B. To store the drug, choose a dark place where the temperature does not exceed 25 ° C.Shelf life is not more than 24 months from the date of production.
Analogues
To similar drugs include first generation antihistamines that have similar characteristics:
- Suprastin,
- Tavegil,
- Dimedrol.
Diazolin is a reliable, safe and tested drug against allergies, which is widely used in medicine.