Nurofen is a potent pharmacological preparation with analgesic and antipyretic effect. Allows to remove puffiness, in short terms to achieve the desired effect. The latter is achieved through the release of different forms of the drug.
Composition, form of release, packing
The main active ingredient is ibuprofen. This is a substance from the group derived from propionic acid. Nurofen is produced in different forms. The tablets are sugar coated. Each contains 200 mg of ibuprofen. Suitable auxiliary substances are sucrose, talc, silicon dioxide, titanium dioxide, stearic acid. In the blister can be 6 or 12 elements.
Effervescent tablets contain the same amount of active ingredient. Still contains in them sucrose, saccharin, sorbitol, citric acid. One plastic tube contains 10 tablets.
Nurofen is sold as a suspension. In 5 ml contains 100 mg of active substance. To produce the syrup, water, glycerol, sodium citrate, flavor, domophane bromide are used.
Suppositories contain 60 mg of ibuprofen and solid fat. Produced in a plastic blister in a cardboard box. It contains 10 candles. Nurofen is also available in the form of a gel or ointment.
Forms of Nurofen
Manufacturer
Nurofen is manufactured in the UK.The manufacturer is Rekitt Benckiser Healsker International Ltd. A company of the same name that accepts claims from manufacturers is located in Moscow.
The drug is produced in different forms and by Reckitt Benckiser. It is located in Australia. There are also two Italian manufacturers: Butts Healsker International, I-Pharma Trento SpA
Indications
Nurofen is used in situations where it is necessary to quickly and effectively remove the pain syndrome. Indications are:
- Headaches and migraines.
- Neuralgia of the trigeminal and facial nerve.
- Acute attack of toothache.
- Discomfort in the spine.
- Radiculitis.
- Shingles.
- Neurology.
- Painful menstruation.
- Elevated body temperature.
Contraindications
Do not use tablets to persons who have problems with the gastrointestinal mucosa. Contraindications include hypersensitivity, peptic ulcer of the stomach and duodenum aspirin asthma, diseases of the optic nerve.
It can not be used for color vision disorders.
Doctors prefer to stop the choice of other medications, if any:
- severe renal failure,
- decompensated heart failure,
- bleeding disorders,
- pregnancy,
- children's age( for tablets).
Mechanism of action
After absorption, the drug moves to organs and places where there is an increased synthesis of enzymes that form prostaglandins. When interacting with active substances, the cycle is interrupted. Non-steroidal anti-inflammatory drug leads to the removal of inflammation, hyperthermic reactions.
Nurofen has a high absorption( connection with plasma proteins reaches 90%).There is a slow penetration into the joint cavity and a delay in the synovial tissue. This creates greater concentrations of the substance than in the plasma.
Instruction for use
The daily dose of the drug for people over 12 years is 1200 mg. It is divided into several receptions depending on the form of medicine used. Usually, 200 mg is prescribed at a time, but according to a doctor's prescription, this dosage can be increased to 400 mg.
Children from 6 to 12 years of age are prescribed not more than 200 mg per day. These medications are taken at regular intervals. The maximum allowable daily dose is 900 mg. Kids are assigned candles. Dosage is selected depending on the weight: 1 kg 5-10 mg. The maximum daily dose is not more than 30 mg per 1 kg.
Instructions for use Nurofen:
Side effects of
If the medicine is taken no more than 2-3 days, side effects are almost not manifested. With more prolonged use, vomiting, meteorism, and the development of erosive and ulcerative symptoms may appear on the part of the gastrointestinal tract. Sometimes there are ulcers on the mucous membrane of the gums, stomatitis, hepatitis, constipation.
With prolonged admission, bleeding may occur, a violation of color vision. When these effects occur, it is recommended that you stop taking the drug and consult a specialist.
Overdose
With a strong increase in dosage, there are severe abdominal pains, drowsiness, depression, headache. Serious poisoning can lead to coma, heart failure, or sudden stopping of breathing.
In all these cases, gastric lavage, use of activated charcoal, alkaline drink is prescribed. The doctor may prescribe symptomatic therapy.
Special instructions
For long-term treatment, it is necessary to monitor the pattern of peripheral blood and the functional state of the urinary system. If there are signs of gastroenterological consequences, then hardware and laboratory methods of investigation are conducted. Including the analysis of feces for latent blood.
During treatment, patients are recommended to abandon all activities requiring increased attention, quick response. In addition, you should refrain from drinking alcohol.
A popular video about the drug Nurofen:
Drug Interaction
Doctors do not recommend combining Nurofen with Aspirin and other nonsteroidal inflammatory drugs. With their simultaneous administration, the anti-inflammatory effect is reduced.
If there is a simultaneous appointment of thrombolytic medications, the risk of bleeding increases. In this case, cyclosporine and gold preparations enhance the effect of the active component on the synthesis occurring in the kidneys. The results can be increased nephrotoxicity.
Reviews of
According to reviews, Nurofen really helps to quickly remove pain and high body temperature. It is noted that the tablets dissolve longer, so the full effect appears in about 30-40 minutes. The most effervescent tablets for adults and candles for children.
Price for Nurofen
The cost of Nurofen depends on the amount of active substance and the form of release. Regular tablets cost from 85 to 250 rubles. Suspension will cost an average of 250 rubles. More expensive is Nurofen Express Forte. One capsule contains 400 mg of active substance. The price of the drug is above 400 rubles.
Analogs
- Moment,
- Maksikold,
- Kalpol,
- Efferlangan,
- Nyz,
- Nimulide.
Cheap
- Ibuprofen,
- Ibuklin,
- Paracetomol,
- Zefikon D.
Analogues of Nurofen
Synonyms of medication
- Nurofen Express Lady,
- Nurofen Long,
- Nurofen Express Forte.
Conditions for dispensing from pharmacies
It is released without the need for a prescription.
Storage and shelf life
Nurofen is not stored in places exposed to direct sunlight. It is better to choose a place where the air temperature does not rise above 25 degrees. Shelf life is three years.