Normax is an antibacterial agent belonging to the group of fluoroquinolones. It is widely used in ophthalmology and ENT-practice. The drug differs in a wide spectrum of action. Often appointed for the treatment of ear diseases.
Composition, form of release, packing
The drug is available in several forms at once. The tablets are film-coated. They are white or almost white. In packages of aluminum foil there are 6 or 10 tablets. All of them are located in a cardboard bundle.
The medicine is also available in the form of drops of the eye and ear. In this case, a 0.3% solution of a clear, colorless color. Can have a slightly yellow color. It is free of any particles. Produced by 5 ml in dark glass bottles, bottles-droppers, which are packed in cardboard packs.
Norfloxacin acts as an active agent. It contains 1 tablet 400 mg, and in 1 ml drops 3 mg. Additional substances are lauryl sulfate sodium, sodium starch glycolate, purified talc, titanium dioxide. Auxiliary substances for drops are:
- water for injection,
- sodium chloride,
- acid glacial acetic,
- benzalkonium chloride.
Drops are made in India. Manufacturer Ipca Laboratories Limited( Ipca Laboratories).
Indications for use
Drops are indicated for inflammation of the mucous membrane of the eye, internal otitis, eustachitis, otitis media and external. The drug is prescribed for corneal ulcers and keratitis.
Can be used to prevent otitis before and after surgery, involving the removal of a foreign body from the ear. If this action was associated with tissue damage.
Tablets are used for bacterial infections of the urinary tract and genitals. Can be prescribed for gastrointestinal diseases and uncomplicated gonorrhea.
As a preventive agent of infectious processes in people with granulocytopenia or travelers diarrhea.
Do not use drugs based on nofloxacin with increased sensitivity to this substance. And also with:
- deficiency of glucose-6-phosphate dehydrogenase.
Mechanism of action
Normox destroys cells of Gram-positive and Gram-negative microorganisms. But the anaerobic group of bacteria remains insensitive to the action of ear drops. The drug inhibits the enzyme necessary for the replication, transcription and pereration of bacterial DNA.When receiving a violation of protein synthesis. This leads to the death of bacteria.
Drops have low systemic absorption. Therefore, the study of pharmacodynamics in this area was not carried out.
Instruction for use
It is prescribed for 1-2 drops in the eye or ear up to 4 times a day. For serious bacterial infections on the first day of use, the dose may be increased to 1-2 drops every 120 minutes. In chronic or acute trachoma, it is possible to apply drugs 2 drops 5 times a day. The duration of treatment can be as long as 2 months.
For infectious diseases of the eyes in the acute phase, 1 drop every 15-30 minutes is used. Depending on the dynamics of improvements, the interval between instillations increases.
According to the instructions tablets are taken at 400 mg twice a day. The duration of such treatment is determined by the doctor individually.
Annotation on the use of the drug Normax in various diseases:
Side effects of
Normax is well tolerated. In rare cases,
- rash may appear.
If such effects occur, the medication is discontinued.
When taking the tablet form of the medicine, the following are possible:
- Allergic manifestations.
- Appearance of feelings of anxiety, increased irritability and sleep disorder.
- Some patients have dizziness and headaches.
- From the gastrointestinal tract, nausea, diarrhea, and heartburn may occur.
No accidental symptoms will appear if the medicine is used accidentally. With a strong increase in dosage, vomiting, headache may occur. There may be a growing sense of anxiety. Treatment consists in sufficient use of a liquid and creation of acid reaction in urine.
The latter is necessary to prevent crystalluria.
No overdose was observed in the ears of this medication.
For 30 minutes after application of the product in the eye, it is not recommended to engage in work that requires special attention. The drug is not allowed for use during pregnancy and lactation. Contraindications have a person under 18 years of age.
In the form of tablets, Normax is used neatly for severe violations of the liver and kidneys. To achieve the maximum therapeutic effect, medications from this group are used 2 hours before antacid drugs are administered or after the same time interval after their use.
Norfloxacin reduces by a quarter the clearance of theophylline. Therefore, with simultaneous use, the dose of the latter decreases. Increases the concentration in the tissues of indirect anticoagulants and cyclosporine. Together with this, the effect of nitrofurans decreases.
Drops for eyes and ears are not compatible with medicines that have physical or chemical acidity values.
Reviews about drops
People use drops to treat barley and conjunctivitis. In many home medicine kits they are for the treatment of otitis and eye diseases. Many have concerns about taking antibacterial drugs. But doctors assure that the drops are not absorbed into the blood, they have local action.
According to reviews, you can understand that more often drops are used, not tablets. Among the positive moments, fast action, availability in pharmacies and at cost are noted.
Among the disadvantages of an uncomfortable bottle and contraindications. Doctors prescribe often a medicine for different forms of otitis, including purulent. Despite the age restrictions, sometimes pediatricians still appoint it to children.
Prices for Normax
The tablets form has a cost of 400 mg on average 150 rubles in Moscow. A bottle of 5 ml drops with a dropper from 70 to 150 rubles.
Synonyms of medication
Analogues of Normaks preparation
Conditions for dispensing from pharmacies
Like any other antibacterial agent, it can be bought by prescription.
Storage conditions and expiration date
Shelf life is 2 years. When buying drops, it is necessary to take into account that after opening the bottle the medicine can be used only for a month. Keep Normaks in a dark place at a temperature of up to 25 degrees.