Nitroglycerin and alcohol: compatibility, lethal dose, consequences

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This drug, like Nitroglycerin, has been known for a long time. It is actively used in medicine for the treatment of cores. It is an antianginal medication used to reduce vascular tone. But holidays, celebrations and jubilees happen in the life of every person, so the question is brewing: is it possible to combine alcohol drinks with taking Nitroglycerin? Is this dangerous and what can it lead to?

Nitroglycerin and alcohol

Preparation Nitroglycerin is a nitrogen-containing substance with venodilating effect. Nitroglycerin refers to substances of an explosive nature, but there is very little of it in the medicine. The drug is used in the therapy of cardiac and arterial pathologies, heart attack, angina pectoris. In addition, a similar drug is used by patients with painful sensations of the gallbladder, acute forms of pancreatitis, intestinal dyskinesia, etc.

Overall, Nitroglycerin has such an effect:

  • Normalizes myocardial activity;
  • Vasodilator effect;
  • Reduces the area affected by myocardial infarction;
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  • Provides muscle heart tissue with additional oxygen;
  • Normalizes the processes of metabolism in the heart.

Nitroglycerin was previously produced only in tablet form. Tablets should be placed under the tongue until they are completely dissolved. Today the drug is produced in the form of a spray, stickers on the gums, drops and capsules, an injection solution. Usually after consumption before the onset of the effect takes about 2 minutes, the effect lasts about an hour.

Interaction

When Nitroglycerin is taken, patients often have a headache that is characteristic of nitrate preparations. This phenomenon is explained by the fact that there is a sharp expansion of vascular beds, including in the brain. Therefore, the vasodilating effect leads to a sharp drop in pressure, hyperemia of the skin and hot flushes. The drug is contraindicated for admission in the presence of cerebral hemorrhages, glaucoma, the state of vascular insufficiency, high ICP, etc.

Nitroglycerin is categorically incompatible with alcohol. Both substances are the most dangerous for the body, so when combined they are likely to irreversible and even lethal consequences. If the patient is prescribed a constant intake of Nitroglycerin, then it is worth considering that you can drink alcohol only after taking the drug for at least 5 hours.

If alcohol has already been drunk and a stenocardic attack has occurred, then this medication should not be taken. It is necessary to call an ambulance, provide fresh air and unbutton the collar on the shirt, so that the patient can breathe easier, however, it is unacceptable to make a decision on taking nitroglycerin immediately after alcohol.

Receiving Nitroglycerin almost instantly relieves the pain syndrome due to lightning action on the nervous system structures. Abuse of this drug and unauthorized increase in dosage is fraught with fatal consequences.

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There is no fixed lethal dose of the drug, because the strength of its effect depends on many factors. One patient may be adversely affected by taking three pills, and the other will not be after a dozen tablets. However, some sources claim that 100 mg of Nitroglycerin per kilogram of body weight are considered fatal. For sure, you can only say that when combined with alcohol, the likelihood of a lethal outcome is high, since both substances mutually reduce the lethal dose of each other.

Consequences of

You can not drink nitroglycerin after alcohol, which is confirmed by all cardiologists, since drug interaction with ethanol can lead to disastrous consequences. Therefore, you can not take alcohol for a four-five-hour period after taking the tablets. First, ethanol multiplies all the side effects of nitroglycerin several times. The headache becomes unbearable, the pressure drop leads to a deep fainting, and then collapse, which is dangerous for lethal consequences.

Secondly, Nitroglycerin components increase the toxicity of alcohol and lower its lethal dose. If earlier, after a bottle of alcohol, the patient felt only intoxication, and then a hangover, then under the influence of the drug with the same amount of alcohol before the hangover state, he may not live to see it.

Conclusions

So, we sum up. The opinion of cardiologists about the combination of nitroglycerin with hot drinks is unequivocal - it is impossible to take alcohol simultaneously with the drug. Drink alcohol is allowed only after 4-5-hour period from the time of taking the medicine. Otherwise, development of undesirable consequences, up to death, is possible. You can take Nitroglycerin only strictly at the doses that are prescribed by the cardiologist, because an overdose can also provoke a fatal outcome.

Any medication in combination with ethanol can cause dangerous consequences for the patient. Nitroglycerin in such compatibility is able to bring the patient to a severe coma, death or a negative effect on the activity of the myocardium. Therefore, you should not abuse this drug and mix it with alcohol, even if the heartaches are strong enough and were taken by surprise during the feast. Alcohol and Nitroglycerin - this is the most deadly combination, which can end badly. In this situation it is recommended to call an ambulance.

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