Among all the variety of antiallergic medicines, we should separately focus on the bamipin, which has proven itself in the treatment of a variety of damage to the body of an allergic nature. Relating to second-generation drugs, bamipin copes with most of the manifestations, affecting the root cause of allergies. The possibility of its use in complex treatment makes it possible to increase the strength and effectiveness of the treatment, which is important in cases of particularly neglected conditions of the patient.
In monotherapy, this drug also proved itself to be good at the expense of rapid absorption of the active substance into the blood of the patient, acting on its receptors responsible for the manifestation of pathological reactions to a certain stimulus( or their group).Ease of use and affordability is considered an important indicator, largely determining the demand for this drug. The use of the inside is caused by the presence of lesions such as urticaria, pollinosis, skin reactions with increased sensitivity to the bites of bloodsucking insects. For external use, a preparation in the form of a gel, which is better manifested in the treatment of conditions such as frostbite of mild tissues, burns of different nature( solar and thermal), is suitable.
Features of the drug
Active substance of the drug bamipin has a healing and restoring effect after 15-20 minutes from the time of its application, the duration of the positive effect is 4-9 hours without repeated application. Thanks to a well-thought-out formula and balanced composition, it is possible to get the most obvious positive result even with a single use of the drug in question, but the therapeutic effect is achieved to a greater extent with a certain course using bamipin. Dosage of the drug and the duration of its use should be determined by the attending dermatologist, who monitors the effect produced during the application and can make the necessary adjustments to the treatment process.
Simple use does not cause difficulties and self-administration of bamipin( the Latin name of the drug Bamipine), it can be purchased at pharmacies of the city and without a doctor's prescription. However, to avoid the possibility of side effects when using and obtaining the fastest positive results, it is recommended to exercise a therapeutic effect only under the guidance of a dermatologist.
Dosage forms
On sale today can be seen in two dosage forms:
- Tablets , which are coated with a rapidly dissoluble under the influence of saliva and gastric juice shell of white and have a rounded shape. Packed tablets in a polymer blister for 10 pieces in each. The blister is in a cardboard box, which also contains instructions for the use of the drug.
- gel used for application to the skin surface. Affected areas before applying the drug in the form of a gel should be previously cleaned, the application of the agent is carried out in a thin layer, rubbing it is not necessary. Due to the rapid absorption of the drug, the beneficial effect of the treatment is noticeable within a short time since the start of bamipin use. The gel is packaged in aluminum tubes with a volume of 30 grams and a cardboard box with instructions for use.
Both dosage forms are easy to use, can be prescribed in childhood and with increased sensitivity of the skin due to the lack of a cumulative effect and a small number of adverse events.
Composition of Bamipin
The active ingredient in the bamipin preparation is bamipin hydrochloride in the tablet form of the agent and bamipin lactate in a gel form for external use.
Price
Cost should be considered an important indicator of the level of demand for a drug, and bamipin can be attributed to antiallergic drugs that have an affordable cost. Price depending on the price policy of the seller can vary between 390 and 580 rubles per package.
Pharmacological action of
The rapidity of the effect of the substance in question is determined by the composition balance. The active substance has a high absorbency when it gets on the skin( in case of using a gel) or in the cavity of the esophagus and then the stomach( in the case of tablets).By blocking H1-histamine receptors, bamipin cope even with particularly neglected manifestations of allergic manifestations. Providing a pronounced anti-allergic, antipruritic and anti-edematous action, this drug reduces the degree of activity of H1-receptors.
The drug also has a calming effect on the skin, weakening the external manifestations of the allergy, restoring the upper layer of the epidermis with greater elasticity, removing its flushing and itching. Burning, accompanying the majority of allergic skin manifestations, is also eliminated even with a single application of the drug.
Pharmacodynamics
Providing an inhibitory effect on histamine blockers, the active substance of Bamipin ensures the elimination of the most characteristic manifestations of allergic reactions of the body. Possessing increased conductivity, the drug substance retains its effect for a certain time, which determines the possibilities for preventing recurrence of acute symptoms of the current lesion.
Cooling effect provides restoration of a comfortable state of skin, elimination of itching and burning of affected areas. Thanks to the thoughtfulness of the formula of this remedy, negative manifestations even with prolonged use of Bamipin are minimal.
Pharmacokinetics
Splitting inside the skin, the drug is excreted from the body with the help of kidneys. The process of accumulation of the active substance is not noted, which causes a small number of adverse events even with prolonged use of this drug.
Indications
Indications for the use of Bamipin in the form of a gel for external use include the following conditions and pathological manifestations:
- urticaria with severe itching and burning of the skin, at which numerous rashes on the skin are noted;
- pollinesis;
- burns - sunny and thermal, with any area of skin damage;
- slight frostbite of the skin;
- dermatoses and eczema of various nature;
- burns from jellyfish;
- bites bloodsucking insects.
The following manifestations can be considered for application of the tablet form of the preparation:
- allergic manifestations in insect bites;
- rashes on the skin, which can be triggered by manifestations of hives;
- increased sensitivity of the skin, accompanied by a rapid appearance of an allergic reaction of different genesis.
Complex effect of the drug in different dosage forms allows to maximize the resulting therapeutic effect.
Instructions for use
The use of Bamipin is quite simple. The application of the gel should be carried out as thin as possible, since this does not prevent the active substance of the drug from actively acting. The application of a fixative dressing and rubbing of the gel is not required. Affected areas of the skin are lubricated with gel completely, getting the drug on the areas of healthy skin does not harm it.
The duration of use of this remedy is determined by the attending physician, on average it is 5-15 days. If the positive dynamics of treatment is inadequate, the duration of Bamipin use may increase.
Adult
For adults, the dosage of the tablet preparation is 100-150 mg per day. Dosage increases with a large area of damage, with a long-term current allergic disease. Duration of admission is determined by the doctor, depending on the effect of treatment.
The gel is applied a thin layer on the pre-cleaned areas of the affected skin 1-2 times a day, the complete absorption of the drug does not require its rubbing.
For infants and children
Bamipin can only be used by children from the age of 12 years, newborns are not recommended for use because of the increased sensitivity of their skin.
In pregnancy, lactation
The use of this drug during child bearing can be prescribed with a predominant positive effect on its use over the likely side effects. During the application of Bamipin, the control of the attending dermatologist is mandatory.
Since the active ingredient has the property of penetrating into breast milk and having a negative effect on the newborn during long-term use, the use of Bamipin during lactation is not recommended.
Contraindications
If excessive skin sensitivity, with frequent allergic manifestations, and if there is severe renal or hepatic insufficiency, Bamipin should not be used.
Side effects of
Side effects when using Bamipin may be considered an increase in the degree of manifestation of the initial symptoms, the appearance of increased skin sensitivity, rashes on it and hyperemia.
Special instructions
In old age, the use of the drug is allowed, but in this case, continuous monitoring of the doctor is required to prevent possible side effects.
Interaction with other drugs
There was no decrease in the activity of the drug when used in complex therapy with other drugs.
Reviews
Many buyers note the availability of the cost of this antiallergic. This allows you to stop on it your choice at the time of purchase. A high degree of effectiveness of the treatment performed with a relatively small number of possible side effects is also widely considered an important advantage of the drug under consideration.
The drug Bamipin is suitable for the elimination of allergic manifestations when used since the age of 12 years. It is noted for its particularly high efficiency in this age category due to the increased activity of the active component of the drug.
Analogues
Drugs with a similar medicinal effect should be considered Sovenenthal, belonging to the same group of antiallergic agents for external use, as well as ointment Mepiramin.
Also good antiallergic drugs are:
- Xylal,
- Clemastin,
- Terfenadine,
- Erius,
- Alerzin,
- Uniderm,
- Zodak,
- Fenistil.