The drug "Naise" belongs to the group of non-steroidal anti-inflammatory drugs( NSAIDs) and is incredibly popular among various population groups. The medicine is very powerful, and doctors recommend taking it solely on prescription. However, the versatility and quick effect of Naise's administration lead to the fact that many pills lie in the medicine cabinet "just in case".Therefore, the compatibility of Naise and alcohol is a very urgent issue. After all, with such popularity, there is always a risk to drink a tablet at the same time or almost next to a dose of alcohol.
What is Nize?
"Nyz" from the NSAID group is available in various forms: suspension, gel( usually used for joints) and tablets. It is the tablets that are most often in the first-aid kits of Russians - thanks to the universal list of indications. They are most dangerous to mix with other medicines and with alcoholic beverages.
Like other non-steroidal anti-inflammatory drugs, Naise has a complex action:
- lowers the temperature;
- stops the inflammatory process;
- relieves pain of various origins( headache, muscle, dental, menstrual, etc.).
The main active substance of Naise is nimesulide, which is among the many NSAIDs( therefore Naise has many analogues).
Once in the body, nimesulide has the following effect:
- inhibits the synthesis of prostate hormone mediators( they carry the nerve impulses that give pain to the cells);
- inhibits platelet aggregation( gluing), that is, liquefies blood;
- inhibits the formation of toxins, that is, it has an antioxidant effect;
- activates glucocorticoid receptors, due to which the anti-inflammatory effect is enhanced.
On the video information about the drug Naiz:
Interaction of alcohol and Naiza
Nayza tablets after ingestion in the gastrointestinal tract are absorbed at a rapid rate - anesthetic effect is manifested after 5-15 minutes( depends on how long and how many people before it ate).
OPINION OF SPECIALISTS!
Elena Malysheva:
"Is Alcoholism Cured? Yes! Use an effective home remedy. .. "
Read more. ..
The highest point of the therapeutic effect of Naise is 1.5-2 hours after swallowing the tablet. The half-life of the main metabolite of nimesulide - 4-hydroxynimidesulide - is from 3 to 5 hours. The most part is excreted with the kidneys( 65%), the rest - with bile.
In the treatment of Naizom, the liver falls first and foremost - the effect of the first passage through the liver is realized. This means that the main metabolism of the drug occurs precisely in the hepatic cells. Therefore, the preparation of nimesulide is considered hepatotoxic, is prohibited to persons with liver diseases and is cautiously prescribed for long-term use. Another danger is the effect on the gastric mucosa: with prolonged use, Naise can provoke an exacerbation of gastrointestinal ailments.
Alcohol has exactly the same toxic effect on the liver, it additionally loads the kidneys, destroys the gastric mucosa, affects speed and coordination. A dangerous effect with the compatibility of alcohol and nimesulide tablets is multiplied many times, so that all the experts convince - the simultaneous intake of alcohol and NSWP, in particular Naiza, - is prohibited!
Possible consequences
The consequences of taking alcoholic beverages of any strength with Nyzes affect all body systems.
The first to suffer are:
- Liver. Liver cells are forced to simultaneously process both medicinal and alcoholic toxins. Enzymes for the cleavage of all poisons simply do not suffice, and toxins linger in the liver, causing irreversible changes. Therefore, for people with cirrhosis and other severe liver diseases, even a single dose of nimesulide tablets is not recommended.
- Gastrointestinal tract. Nyz and alcohol both irritate mucous, so a double blow inevitably provokes heartburn, abdominal pain, even nausea and vomiting. And if the alcohol dose is greatly exceeded, there is a risk of poisoning, and nimesulid only enhances this possibility.
- Heart and blood vessels. A portion of alcohol inevitably dilates blood vessels, and Naise reduces blood clotting. Such a "tandem" in the presence of diseases can lead to internal bleeding - for example, with peptic ulcer.
The combination of alcohol and nimesulide preparations also adversely affects the kidneys, which are forced to process and excrete an increased "dose" of toxins in the urine. The alcoholic-medicinal effect is very harmful, and for the nervous system - weakened attention, delayed reaction, coordination disorders are doubled due to a similar effect of ethanol and nimesulide.
Rules for combining
All comments on the combination of Naize and alcoholic drinks say only one thing: you can not drink tablets and alcohol together, they are not compatible. More precise instructions concern the combination of alcohol and non-steroidal anti-inflammatory drugs, the group of which includes nimesulide.
The main condition - do not drink tablets and alcohol, while in the blood there are still traces of at least one of these funds.
From here you can derive several rules.
- The average time of alcohol breakdown in blood, depending on the portion, strength of the drink and the weight of a person, is 5-12 hours. Therefore, you can drink an anesthetic( Naise) only after this time. And to treat tablets nimesulida hangover in general is strictly prohibited.
- All decay products of nimesulide are excreted from the body in 5 hours. This is the answer to the question, through how much you can drink alcohol.
- Often, Nyz is appointed a course. If you can not interrupt the treatment course and for some reason need to drink, some doctors advise before a meal to take a pill omeprazole to protect the stomach mucosa. However, this "protection" is not suitable for all patients, and it is better to specify in advance all the alcoholic nuances from the doctor who issued the prescription for Naise.
Conclusions
In the question whether it is possible to combine alcohol and Naise tablets, experts are unanimous - it is impossible in any case. Especially dangerous is the reception of alcohol on the background of long-term treatment with NSAIDs.
Therefore, when taking Naise and any alcohol should be observed a sufficient time interval. And if the doctor has prescribed a long course of NSAIDs, it is important to take regular examinations to prevent complications. Otherwise, even a single dose of alcohol, after the end of therapy, can cause unpleasant symptoms and exacerbation of chronic diseases.