The drug is strong, it has the characteristic of causing drug addiction, so caution is required when using. Injections are used only in a hospital in the presence of an anesthesiologist. So, today we will talk about plasters, injections of Fentanyl, their price, dosage, prescription and instructions for use.
Features of the preparation
The drug increases the pain threshold. It introduces disturbances into the system of transmission of excitation along paths that form a sensation of pain. Produces a hypnotic effect.
Reduces blood flow in the kidneys, intestinal peristalsis. Smooth muscles increase the tone in the area:
- of the bladder,
- bile duct,
- sphincter.
Composition
The drug contains active ingredient fentanyl. Auxiliary components:
- ethylene-vinyl acetate copolymer,
- hydroxyethylcellulose.
Pro Forms and prices for Fentanyl in Russia you will find below.
Forms of release Fentanyl
The preparation Fentanyl is issued as:
- injection solution:
- system for intravenous administration, the cost of 2300 rubles.and higher;
- Fentanyl in ampoules for intramuscular use, the cost of 2300 rubles.and higher;
- for the external use of the transdermal therapeutic system Fentanyl, the package price is approximately 480 ÷ 720 rub.
About the mechanism of action of Fentanyl and the duration of the action you will learn further.
Pharmacological action
Anesthetic drug. Has narcotic properties. The drug manifests itself quickly, but has a short-term effect.
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The opinion of doctors. .. & gt; & gt;
The effect of anesthesia develops:
- When administered intramuscularly after a quarter of an hour, the injection lasts up to 30 minutes.
- In the treatment through intravenous administration of fentanyl, the drug is effective after three minutes.
Pharmacodynamics
Synthetic analgesic with the presence of narcotic action. Therapeutic effect is sedative and analgesic.
Pharmacokinetics
Chemical transformations of the drug occur in the liver. The remedy is for the most part excreted in urine:
- 10% - the substance leaves without changing its formula,
- 75% - a drug falling into the urine in the form of metabolites;
- the remainder of the substance converted to metabolites, leaves the body together with feces.
Indications
Applied:
- as an anesthetic for operations, alone or additionally, along with other medicines;
- for relief of pain in the postoperative period,
- for elimination of pain in diseases:
- myocardial infarction,
- of hepatic colic,
- lung infarction,
- renal colic,
- before operation( premedication).
A patch with fentanyl is used:
- if non-occlusive pain occurs,
- to relieve the condition with systematic pain in patients with cancer.
Instruction for use
The tool is used:- for surgical anesthesia:
- adults are injected intravenously every half hour 0.05 ÷ 0.2 mg,
- for children intravenously 0.01 ÷ 0.15 mg per kilogram of weight, maintenance of anesthesia during surgery 0.001 ÷ 0.002 mg per kilogram of body weight;
- in preparation for anesthesia for surgical intervention:
- for adults - intravenous infusion of 0.05 ÷ 0.1 mg( together with droperidol 2.5 ÷ 5 mg),
- for children - 0.002 mg per kilogram of weight intramuscularly.
Contraindications Do not apply for such indications: - addiction,
- lung infarction,
- hypersensitivity to the drug,
- for caesarean section,
- , the patient experiences depression of the respiratory center,
- hypertension,
- after operations on reproductive organs in women in the period associated withwith pregnancy;
- if the patient suffers from bronchial asthma.
Side effects of
Possible consequences:
- bronchospasm,
- respiratory depression,
- muscle rigidity,
- bradycardia.
Special instructions
Cautions
Some cautions regarding the use of the medicine. If a patch is used, then you should not simultaneously allow direct thermal exposure:
- exposure to sunlight,
- application of a heating pad,
- visit to the sauna.
Caution is used to treat patients in whom:
- is a children's age,
- deficient liver and kidney function,
- impaired consciousness,
- bradyarrhythmia,
- state of coma,
- , elderly age,
- are diagnosed by education in the brain.
Do not prescribe if the patient has acute pain in the postoperative period.
Abolish the drug gradually. To draw attention to the possibility of a secondary respiratory depression in asthenic patients, if a drug is administered in large doses.
Overdosing
When exceeding the highest single dose of fentanyl( overdose):
- decrease in urinary flow,
- pupillary constriction,
- dizziness,
- pulmonary edema,
- hallucinations,
- hypoxia,
- respiratory arrest,
- reduction of gastric juice,
- blurred vision,
- bradycardia,
- metabolic slowdown,
- deterioration of peristalsis,
- cardiac arrest.
Reviews
Users give a high rating to the drug in the form of a patch. It is noted that it is effective against pain, it is convenient in application.
Patients used it at home in the period after surgery. One thing that is classified as a minus is its price.
Analogues
The agent can be replaced with the preparations:
- Fendivia,
- Dolforin,
- Matrix,
- Lulaldin,
- Durogesic,
- Fentadol.
- addiction,
- lung infarction,
- hypersensitivity to the drug,
- for caesarean section,
- , the patient experiences depression of the respiratory center,
- hypertension,
- after operations on reproductive organs in women in the period associated withwith pregnancy;
- if the patient suffers from bronchial asthma.
Side effects of
Possible consequences:
- bronchospasm,
- respiratory depression,
- muscle rigidity,
- bradycardia.
Special instructions
Cautions
Some cautions regarding the use of the medicine. If a patch is used, then you should not simultaneously allow direct thermal exposure:
- exposure to sunlight,
- application of a heating pad,
- visit to the sauna.
Caution is used to treat patients in whom:
- is a children's age,
- deficient liver and kidney function,
- impaired consciousness,
- bradyarrhythmia,
- state of coma,
- , elderly age,
- are diagnosed by education in the brain.
Do not prescribe if the patient has acute pain in the postoperative period.
Abolish the drug gradually. To draw attention to the possibility of a secondary respiratory depression in asthenic patients, if a drug is administered in large doses.
Overdosing
When exceeding the highest single dose of fentanyl( overdose):
- decrease in urinary flow,
- pupillary constriction,
- dizziness,
- pulmonary edema,
- hallucinations,
- hypoxia,
- respiratory arrest,
- reduction of gastric juice,
- blurred vision,
- bradycardia,
- metabolic slowdown,
- deterioration of peristalsis,
- cardiac arrest.
Reviews
Users give a high rating to the drug in the form of a patch. It is noted that it is effective against pain, it is convenient in application.
Patients used it at home in the period after surgery. One thing that is classified as a minus is its price.
Analogues
The agent can be replaced with the preparations:
- Fendivia,
- Dolforin,
- Matrix,
- Lulaldin,
- Durogesic,
- Fentadol.