Ointment The fluorocort is intended for external use, manufactured by the Hungarian pharmaceutical company Gedeon Richter, refers to hormonal drugs for the treatment of non-infectious skin diseases. We will today consider the instruction on the use of the drug, reviews about the ointment Fluorocort, its price and analogues.
Features of the drug
Fluorocort is a glucocorticosteroid drug similar to hormones that are produced by the adrenal glands. With topical use, this hormonal drug does not have systemic effects.
Composition Fluorocorte
Ointment Fluorocort is a homogeneous mass of white color, odorless. The active component is a synthetic fluorinated glucocorticosteroid triamcinolone acetonide.
Dosage forms
The product goes on sale in aluminum tubes weighing 15 g, the price for one package is 210 - 250 rubles.
Pharmacological action
Fluorocort is distinguished by anti-inflammatory, anti-allergic action. The drug reduces puffiness of tissues, has antipruritic effect.
Farmakodinamika
Triamcinolone acetonide penetrates into the cell, where it interacts with DNA sites responsible for the synthesis of lipocortins. An increase in the production of lipocortins inhibits the synthesis of arachidonic acid, which is the source of the formation of inflammatory factors - prostaglandins, leukotrienes, prostacyclins, thromboxane.
Under the action of triamcinolone:
- , the permeability of the walls of the blood vessels decreases;
- decreases the synthesis of histamine, a factor that promotes an allergic reaction;
- decreases the concentration of bradykinin - a substance releasing histamine, stimulating the synthesis of prostaglandins.
Pharmacokinetics
With topical use, Fluorocort is evenly distributed, reaching deep layers of the skin. In the general bloodstream, the agent does not fall into a thin layer when applied to the skin.
In the systemic circulation, the fluorocorte penetrates if used under an occlusive dressing. Metabolizes triamcinolone in the liver, excreted by the kidneys. The elimination half-life is 3.5-5 hours. In tissues, triamcinolone is detected after 18 to 36 hours after the last use of the ointment.
The following are the indications for the use of the Fluorocort.
Indications
Fluorocort is used to treat:
- atopic dermatitis;
- contact dermatitis;
- of bullous dermatitis;
- of solar dermatitis;
- of balanitis;
- pemphigus vulgaris;
- eczema;
- of Leiner disease;
- of psoriasis;
- vitiligo;
- of red lichen planus;
- toxic erythema;
- of external otitis media;
- of insect bites.
The role of Fluorocort in the fight against alopecia is described by the video below:
Instructions for use
- Fluorocorte lubricate the skin 2-3 times a day. The daily expenditure of the ointment should not exceed 15 g. The duration of treatment should be 5-10 days.
- The course can be extended up to 25 days, the maximum duration of the ointment application is 4 weeks.
- Fluorocort can be used for an occlusive( airtight) bandage. In this case, the period of use of the ointment with a therapeutic purpose does not exceed 10 days, the daily dose is 10 g. For children, the elderly ointment is not applied under the occlusive dressing.
Contraindications
Fluorocortex is not used to treat children under 2 years. During pregnancy, during breastfeeding, Fluorocort Ointment is used only on the advice of a doctor.
No ointment for diseases such as:
- skin tuberculosis;
- acne;
- perioral( perioral) dermatitis;
- rosacea;
- trophic ulcers of lower extremities.
Side effects of
Side effects occur if the instructions for use - overdose of the drug or if the duration of treatment exceeds 1 month. Side effects are manifested:
- by skin irritation, dryness, itching;
- folliculitis;
- excess hair growth;
- with allergic dermatitis;
- by perioral dermatitis;
- sweating;
- poor wound healing;
- by hypopigmentation;
- by skin maceration;
- atrophy of the skin.
Prolonged treatment courses can cause systemic changes:
- osteoporosis;
- hypokalemia;
- gastric bleeding;
- halting growth in children;
- cataract, glaucoma;
- inflammation of the pancreas;
- changes in blood sugar;
- convulsions, insomnia;
- mental disorders.
Special instructions
- The fluorocort can not be applied to the skin around the eyes,
- should be used for superficial skin lesions.
In case of side effects, the drug is canceled.
Interactions
The effect of ointment is enhanced by oral administration of hormonal drugs in tablets.
Reviews
Most reviews of consumers show a high efficacy of the drug, but the overall picture is somewhat spoiled by the side effects that this hormone drug often meets.
Side effects include dry skin and the appearance of pustules, which can be explained by an overdose, as well as the lack of therapeutic effect.
On whether there is a cheaper Ftorokort analogue, we will tell below.
Analogs
Analog in group and active component of ointment Fluorocort is the Kenalog. Replace Fluorocort can be treated with a similar action:
- Triacort,
- Afloderm,
- Lokoid,
- Cinaph,
- Polcortolone,
- Dermovaytom,
- Latikor,
- Powermart,
- .
On how to use Fluorocort and its analogues in vitiligo, this video will tell: