Ammifurine( photo)
Dosage forms
Today Ammifurin is available in two main dosage forms, which are easy to use, quickly absorbed by the body and when exposed to a minimal amount of negative manifestations on the body. In pharmacies the product is presented in the form of tablets and a solution.
Composition of Ammifurin
The main active substance of the drug under consideration is a plant substance - Ami of a large fruit furokumariny. This plant has a pronounced effect when applied to the skin by rapid penetration into the upper layer of the epidermis, rapid elimination of the delay in the production of melatonin in the skin.
1 tablet contains about 30 mg of ammifurin, in 1 ml of the solution, 20 mg of the active ingredient.
Tablets have a rounded shape, a white film that dissolves easily under the influence of saliva and gastric juice. The solution is transparent, has no sediment even after prolonged settling. In the packing of tablets there are 50 pieces, they are placed in a container of glass of dark color and in cardboard packing with the accompanying instruction.
The prices of
The cost of the drug varies slightly among different sellers, but on average it makes up 815-845 rubles for a solution, for a tablet product - 700-735 rubles per packing. Referring to photosensitizers, Ammufulin copes even with significant manifestations of skin lesions, which are manifested in the increased tendency of the skin to become inflamed, the appearance of rashes and redness on their surface, and the appearance of skin hypersensitivity.
Pharmacodynamics
Due to the rapid absorption of the active substance, almost instantaneous action of the drug on the skin occurs at the sites of its destruction, while the degree of manifestation of the most characteristic symptoms of the lesion decreases. The most important indicator of the effect of the drug on the affected areas of the skin, devoid of the necessary degree of pigmentation, is precisely the rate of the first positive results of the treatment.
Skin sensitization with activation of the process of melatonin production is accompanied by an improvement in the appearance of the skin, elimination of its cosmetic defects in the form of white unpainted spots.
Pharmacokinetics
After complete disintegration of the active substance of the agent, the residual particles are neutralized by means of the liver and kidneys. Remains of the drug are excreted in a vein form with urine in the kidneys.
Indications
As the drug Ammifurin has proved to be an effective remedy for external use with numerous skin lesions accompanied by changes in the appearance of the skin and its functionality, its use makes it possible to neutralize as quickly as possible such manifestations as the lack of necessary pigmentation in certain areas of skin, the appearance of crackingepidermis, inflammatory processes.
The indications for the use of Ammifurin include the following conditions and pathological processes on the skin:
- vitiligo;
- psoriasis;
- alopecia;
- mushroom mycosis.
Any damage to the integrity of the skin that leads to a violation of the basic functions of the skin( protective and ongoing) can be cured with the integrated use of the drug in question with a wide range of applications. Perfectly coping with the most characteristic symptoms, Ammifurin also removes the unpleasant sensations associated with the underlying disease - dryness and tightness of the skin, its increased sensitivity, the appearance of uncharacteristic rashes for a healthy epidermis.
Instruction for use
Ease of use Ammifurin allows the use of this drug for almost everyone;and the solution and tablet form of the drug are rapidly absorbed by the mucous or skin surface, eliminating the obvious signs of the underlying lesion and returning the skin an attractive appearance.
The main rule of application of this drug is the compliance with the dosage prescribed by the attending dermatologist. And although the drug can be sold even without a prescription, its use will bring a pronounced positive effect only if the size of a single dose of application( or ingestion when taking tablets) and the period of application were chosen correctly. For this doctor takes into account such indicators of the patient's health, as neglect of the pathological process, the general health of the patient, the presence of associated organic pathologies, as well as the degree of susceptibility of the body to the treatment.
Adult
For adults, a single application dosage is 0.1-1 g of ointment, different amounts of substance should be used for different lesion areas. If the drug gets into areas with healthy skin, no negative effect is observed.
Apply the solution 1-3 times a day, the skin is pre-cleaned. Duration of use depends on the availability of positive results in treatment and is for adults from 1.5 to 4 weeks of continuous use.
To enhance the effect of this tool, it is recommended to combine its use with ultraviolet irradiation, which allows to accelerate the activity of cells that produce melatonin. A greater propensity to quickly perceive the drug in question is noted in persons with dark skin, prone to purchase a quick tan.
For children and newborns
In early childhood, the drug can be used, but with increased caution. Control of a dermatologist will avoid possible negative manifestations when using this medication. Dosage of use in this case, newborns and children under 1 year) is not more than 0.1 g of the drug per day with external application.
In pregnancy and lactation,
During pregnancy and at the time of newborn breastfeeding, the use of the drug may be continued. However, caution and accuracy should also be followed - if any allergic reaction occurs, Ammifurin should be discontinued or replaced with a similar one.
Contraindications
Contraindications to the use of Ammifurin include the hypersensitivity of the skin to the components of the drug, the appearance of rashes and redness. Renal failure can also cause negative symptoms during treatment with Ammifurin.
Side effects of
The use of this regenerative agent for external use can lead to more severe symptoms, the appearance of severe dry skin, redness of the skin and increase its sensitivity. Also, side effects include:
- cardialgia;
- attacks of tachycardia;
- appearance of nausea and vomiting;
- dizziness;
- deterioration of orientation in space.
The listed adverse events may occur in different patients in varying degrees.
Special instructions
- When using Ammifurin in the elderly, it is likely to increase the number of adverse events that are accompanied by an increase in the number of inflamed tissues.
- A greater degree of susceptibility to active substances in the preparation is observed at a younger age and with unopened stages of the disease.
- With increased sensitivity to the components, it is likely that necrosis foci are present, and the use of Ammifurin should be urgently discontinued and replaced with a similar one having a similar effect.
Interaction with other drugs
In the complex treatment of these manifestations, the drug Ammifurin increases its effect, which allows you to assign it together with drugs of similar manifestation. To stimulate the immune system of the skin and accelerate the regenerative processes in the epidermis, it is recommended to use the stimulating protective properties of the body preparations.
Reviews
Since Ammifurin perfectly copes with the main symptoms in many skin lesions, many patients note first and foremost the high degree of effectiveness of this remedy. At the same time, a relatively small number of adverse events make it possible to administer Ammifurin even with increased sensitivity of the skin, in childhood.
The cost of the tool is fairly affordable, which is also important for most buyers.
Analogs
Beroxane, Dyvobed, Psoriaten - listed external agents are also used in the treatment of many skin lesions.
In this video, the doctor tells about Ammifurin and other vitiligo medications:
