Corvalol is a sedative, popular in the countries of the former USSR, but banned in Poland, Germany, the USA, Norway, Lithuania. The prohibitive measures are taken because of the presence of the psychoactive compound phenobarbital in Corvalol, as well as the toxic bromine-containing component.
What makes the tool popular with Russians who drink an average of 40 rail tank cars per year? And today we will talk in more detail about the indications and instructions for the use of drops and tablets Corvalol, its price, reviews, composition, analogues.
Features of the drug
Combined medicine Corvalol shows a sedative, vasodilating action, is used against insomnia, as a soothing drug for stress, emotional stress. The Ministry of Health of the Russian Federation has recognized Corvalol as a drug with a low content of psychoactive substance, authorized for sale without a prescription, planning in the future to refuse the appointment of patients to this drug, replacing it with more modern medicines.
The harm and benefit of Corvalol will tell this video:
Composition of Corvalol
Active ingredients of the drug Corvalol:
- ethyl ester of alpha-bromovaleric acid( ethyl bromoisovalericanate);
- phenobarbital;
- oil of peppermint leaves.
Corvalol in the drops serve as:
- ethyl alcohol;
- caustic soda;
- purified water.
Auxiliary components in tablets - betadix, lactose, potato starch, magnesium salts.
For prevention and treatment of cardiovascular diseases, our readers advise the drug "NORMALIFE".This is a natural remedy that affects the cause of the disease, completely preventing the risk of getting a heart attack or stroke. NORMALIFE has no contraindications and begins to act within a few hours after its use. The effectiveness and safety of the drug has been repeatedly proven by clinical studies and long-term therapeutic experience.
The opinion of doctors. .. & gt; & gt;
Dosage forms
Corvalol is produced in alcohol drops, tablets for resorption sublingually( under the tongue).Tablets are packed in blisters of 10, 30 and 50 pieces.
Alcohol drops are packaged in dark glass bottles with a capacity of 15 ml, 25 ml, 50 ml. Spirituous tincture differs strong specific aroma. The price of Corvalol tincture is on average:
- for 15 ml capacity - 16 rubles;
- 25 ml - 23 rubles;
- 50 ml - 33 rubles.
Prices for Corvalol may vary from 9 to 120 rubles. The cost of 10 tablets Corvalol is 18 rubles.
Pharmacological action
Corvalol belongs to the group of sedatives, it is a combined preparation showing a calming, spasmolytic, vasodilating action that contributes to the normalization of sleep.
The video below will describe both the composition and properties of Corvalol:
Farmakodinamika
The properties of Corvalol are determined by the total effect of its active components.
- The main active ingredient is ethyl bromizovalerianate. This compound eliminates the spasm of the smooth muscles of the internal organs, soothes, relaxes the nervous system.
- Phenobarbital has the ability to act on the central nervous system, directly removing the excitation of the nerve centers of the brain. The soothing effect of phenobarbital is less pronounced.
- Peppermint oil, irritating the "cold" sensitive nerve endings of the mouth, selectively dilates the vessels of the brain, coronary vessels that feed the heart muscle. The oil shows choleretic, antiseptic activity, helps to eliminate flatulence.
Pharmacokinetics
The effect of the drug in tablets begins in the oral cavity. The positive effect of the medication on the patient's well-being with resorption of the tablet under the tongue manifests itself almost instantly.
The effect of Corvalol's action when taken in the form of drops is visible after 10-30 minutes. The duration of the drug when taken in tablets and drops is 6 hours.
Of the active substances Corvalol most studied the pharmacokinetics of phenobarbital. This compound is well absorbed, has the ability to accumulate in the body. The half-life of phenobarbital is 2-4 days. The compound decomposes into simple components in the liver, is excreted by the kidneys in the form of glucuronide, in part( 25%) unchanged.
From what helps Corvalolum, how to take it, we will tell further.
Indications
- Functional disorders of the cardiovascular system;
- sleep disturbances;
- neurosis-like conditions;
- initial stages of hypertension, spasms of the heart vessels;
- tachycardia;
- intestinal spasms.
Instructions for use
- Adults Corvalol tablets are prescribed 1 tablet with a tachycardia attack, spasms of blood vessels. If necessary, the dosage of the drug can be increased to 3 tablets.
- Alcoholic tincture of Corvalol is taken with water 10-30 drops or a piece of sugar. The maximum one-time reception of tincture should not exceed 50 drops.
The doctor chooses the treatment scheme individually. The drug is taken no more than 3 times a day, the duration of treatment depends on the patient's condition, the dynamics of the disease.
To give children medicine can be no more than once a day, in the amount of 3-15 drops. Treatment should be controlled by a doctor because of the lack of data on the effect of Corvalol on the children's body.
Contraindications
- Hypersensitivity to components of the medication;
- age under 18 years;
- pregnancy, lactation;
- lactose intolerance;
- heart disease;
- renal, hepatic impairment.
Corvalol is not allowed in pregnancy due to the ability of its phenobarbital component to penetrate the placental barrier, to have a teratogenic effect on the fetus. Taking medication during pregnancy can provoke the appearance of congenital anatomical malformations, a violation of the formation of internal organs.
Side effects of
The most dangerous side effect of Corvalol is a psychological addiction to phenobarbital. And, if the physical dependence on phenobarbital is poorly expressed, then the psychic dependence is formed quickly.
Psychic dependence forces everywhere to take with itself a treasured vial, at all inconvenient situations to resort to its magic calming effect, simultaneously increasing in the body the concentration of bromine contained in ethyl bromizovalerianate.
Symptoms of bromide poisoning are:
- inhibition of the central nervous system;
- a propensity for depression;
- confusion;
- impaired coordination.
Admission of Corvalol is capable of causing side effects from:
- of the nervous system - inability to concentrate, dizziness, drowsiness;
- cardiovascular system - bradycardia;
- digestive system - nausea, vomiting, stomach pain.
Special instructions
The drug can not be combined with alcohol, mainly because of the presence of phenobarbital in its composition. This component is destroyed in the liver, like alcohol, which leads to increased stress on it.
Phenobarbital, part of Corvalol, has the property of enhancing the action of sedatives. With care combine Corvalol with sleeping pills, analgesics, it is not recommended to drink the drug with drugs metabolizing in the liver - hormonal drugs, antibiotics, contraceptives.
Overdose
Exceeding the dose of Corvalol is accompanied by a drop in blood pressure, dizziness, inhibition of brain activity. If the symptoms of an overdose of Corvalol do not pass after the drug is discontinued, the patient is washed with a stomach, called an ambulance.
In severe conditions, it is possible:
- neuromuscular muscle compliance disorder - ataxia;
- violation of heart rate, heart rate increase;
- sharp drop in blood pressure;
- loss of consciousness, coma.
Reviews
- More than 90% of consumers who resorted to treatment with Corvalol, note its calming effect on the nervous system, the ability to normalize sleep, to calm a strong heartbeat.
- Among negative reviews, the presence of alcohol in the composition of drops is noted, the possibility of getting used to phenobarbital and ethyl alcohol. The reality of this threat is manifested in the gradual increase in the dose of the drug.
- Almost always starting with a small dose of 10-15 drops, patients gradually bring a single dose of Corvalol to 60 drops, indicating an increase in tolerance to the drug and indicates the formation of a real drug addiction.
Analogues
Coralol analogs include Valocordin, Valecard-Health, Corvaldin, Reladorm.
On the narcological properties of Corvalol will tell this video: