Urolithiasis is extremely diverse and may occur in different ways. In some cases, the patient does not even understand the presence of sand and stones in the kidney or bladder. In others, the deposition of stones is accompanied by swelling of the tissues, muscle spasm and other complications. Rovatinex, being a phytopreparation, has a mild spasmolytic and diuretic effect in any course of the disease.
Rovatineks
The drug is not a universal drug, of course, but it works in most cases. The fact is that the active substances in its composition contribute to the dissolution of calcium salts, and according to statistics, they account for 80% of cases of urolithiasis.
The latter can be deposited in the kidneys, bladder, urinary tract. They have a variety of shapes and sizes, are formed at any age, although most often observed in men over 50. There are phosphate, oxalate - most often, and carbonate calcium stones.
There are other important qualities:
- spasmolytic effect - the drug improves blood flow in the kidney, raises diuresis, which reduces pain in renal colic. But the main thing - improves the passage of calcium calculus along the urinary tract;
- anti-inflammatory - reduces edema of tissues, which reduces spasm of smooth muscles, and, consequently, relieves pain syndrome;
- antimicrobial action - and rovatinex is effective to a number of both gram-positive and gram-negative microorganisms;
- urodynamic - the most sensitive to the action of the drug is the upper urinary tract. This feature is used by assigning rovatinex for the fastest withdrawal of sand, after applying shock wave lithotripsy;
- protective - the drug increases the content of glucuronic acid in urine, which leads to the dissolution of calcium salts;
- preventive - prevents the deposition of calcifications in both the kidneys and the bladder.
According to Dzeranov N.K, the use of rovatinex in urolithiasis increases the proportion of patients completely discharged from calcitans from 24 to 67%.
Composition
Rovatinex is a phytopreparation made entirely from natural plant material. The medicine is standardized, that is, it contains the exact amount of active and supplementary substances.
To active are:
- anethole - 4 mg in each dose;
- borneol - 10 mg;
- camphene - 15 mg;
- alpha, beta-pinene - 312 mg;
- fenghon - 4 mg;
- cineole - 3 mg.
Capsule shell contains:
- gelatin - common food;
- glycerol - 85%;
- ethylparahydroxybenzoate sodium;
- dyes.
The shell is classified as enteric-soluble. It ensures that the drug reaches the organs.
Form
The medicine is available only in the form of capsules: round, covered with gelatinous shell of a greenish-yellow or pale yellow hue. The contents of the capsules are liquid, has a strong vegetable smell, reminiscent of the smell of coniferous trees.
Packing includes 50 or 100 capsules:
- The packing price in 50 tablets ranges from 1295 to 1558 r.
- Packing in 100 capsules is much less common in Russian pharmacies. The cost is from 2895 r.
Operating principle
The main task of the drug is to remove or dissolve calcium salts, that is, in essence - to provide a dissolving medium. The role of the solvent for calcinates in the human body is performed by glucuronides and glucuronic acid. With urolithiasis, the level of these substances in the urine is too low, and calcium salts do not interfere with deposition.
Rovatinex contains terpenes - the same borneol or cineole. As soon as they enter the intestine - the shell dissolves right here, they begin to transform into glucuronides, after all, the compounds are in the urine and dissolve the calcium deposits in the kidneys or bladder.
The same effect allows you to remove stones. Large concrements are gradually destroyed by the action of glucuronic acid and are excreted in the urine. A spasmolytic action of the drug prevents and reduces pain during the movement of stones.
The antimicrobial and anti-inflammatory effects of rovatinex are small - inflammation is not the main remedy. However, with urolithiasis, terpenes reduce swelling of the tissue, which in itself facilitates the passage of stones, and prevents stagnation of urine. Namely, the latter creates a favorable environment for the development of pathogenic microflora.
The video composition, the principle of action and effectiveness of the drug Rovatinex:
Indications
The drug is prescribed for ailments associated with the presence of calcium deposits or the danger of their appearance:
- prophylaxis of urolithiasis and nephrolithiasis;
- relapse prevention after surgery to remove calcifications;
- treatment of stones - as an accompanying drug on the background of the main course;
- chronic inflammation of the urinary tract - in this case, the antimicrobial effect of the drug is important. Used outside the period of exacerbation;
- renal colic - treatment is carried out under the supervision of an observant physician, since the diuretic and antispasmodic effect of the drug can provoke colic;
- is prescribed after acute inflammation of the urinary tract as a preventive agent.
Instruction for use
Terpenes are active substances of rovatinex, have been used in clinical practice for a long time. Side effects are minimal, and tolerability, on the contrary, is very high. However, the drug should not be prescribed for children: rovatinex is indicated for use in treating children from 6 years of age.
- Adults and children over 14 years of age are prescribed 1-2 capsules three times a day. With exacerbations - renal colic, the dose may be increased to 2-3 capsules 4-5 times a day. After the normalization of the condition, the dosage is reduced.
- Children from 6 to 14 years are prescribed no more than 1 capsule twice a knock.
- After crushing calcitants, the medication is prescribed for the prompt removal of fragments. Take rovatinex 2 capsules three times a day.
The course is usually 30 days. For preventive purposes, the course is repeated, but not earlier than 2 months later.
The medication is consumed before meals - swallowed, always washed down with plenty of water. During the entire course of treatment, copious drinking is an indispensable part of therapy.
Side effects of
Side effects occur extremely rarely and are poorly expressed. More often than not, it is some discomfort in the stomach, which runs on its own and does not require intervention. Vomiting is possible.
During the entire period of drug use, only 2 cases of drug intolerance were noted. The reason is not fixed.
Contraindications
The list of contraindications is small:
- hypersensitivity to any active component;
- hypersensitivity of capsule-forming capsules;
- first trimester of pregnancy;
- lactation period;
- children's age - up to 6 years.
Do not prescribe the drug for acute colic, anuria, since its effect can aggravate the situation. It makes no sense to use it in case of serious infectious diseases, since in this case its antimicrobial effect is not enough.
In addition, the value should take into account the interaction of the drug with other medicines. So, rovatineks changes the activity of anticoagulants - warfarin, thrombostop. The same effect it has on drugs, in the metabolism of which hepatic enzymes are involved - this, for example, almost all antidepressants.
Special instructions
In the treatment of rovatineksom only recommendation is a plentiful drink. And for the destruction of calcium stones, and for their withdrawal requires an additional volume of fluid.
Despite the overall safety of the drug, an overdose can lead to abnormalities in the functioning of the cardiovascular system, respiratory tract. If the capsules have been taken recently, a gastric lavage is prescribed. If the time has passed enough, symptomatic therapy is performed.
Analogues
Rovatinex is manufactured only by the Irish company Rova Pharmaceuticals Ltd. It has no analogues in composition.
There are a number of drugs that have a similar effect, but with other active components:
- afal - resorption tablets;
- kanefron H;
- Lespeflan - solution and extract;
- flaronin;
- cystone;
- RENEL - homeopathic tablets.
Reviews
According to the research conducted by the Federal Agency for Morphology of Urology of the Ministry of Health and Social Development of the Russian Federation, rovatinex promotes more complete excretion and dissolution of calcic stones. At its use during treatment the share of the recovered has increased from 24 to 67%.
Rovatex is a truly effective remedy for the removal and dissolution of calcium stones. The drug has virtually no contraindications, and side effects are extremely rare.