Modern antihistamines, which have a small sedative effect and provide a rapid elimination of the most obvious manifestations of allergic reactions, are now available in a wide variety. They can be distinguished by their ease of use, the balance of the composition and the minimum number of adverse events with prolonged use. And among the effective and safe means, it should be especially emphasized Clemastin, which has proven itself in eliminating allergy symptoms such as itching and burning of the skin, the appearance of hyperemia and increased sensitivity of the skin, and a decrease in the permeability of capillaries, which suggests the possibility of its appointmentespecially neglected cases of allergies of different nature.
With the help of the Clemastig you can quickly remove puffiness of the skin, eliminate the manifestations of such common lesions as hives, dermatitis and eczema. Thanks to the thoughtfulness of the composition, this drug is well tolerated even by people with increased sensitivity to the medicinal constituents of the drug, and the opportunity to use it in complex therapy makes it possible to speed up the process of removing the main symptomatology of allergic diseases.
Features of the drug
As a last-generation antihistamine drug, Clemastin, which has the Latin name Clemastine, belongs to the group of the most effective medical devices with a wide range of applications. This drug is produced in Poland. Presented in several most convenient dosage forms( in the form of tablets, syrup and solution for injection), Clemastin is easy to apply, its dosage is determined in accordance with the diagnosis and recommendations of the treating doctor.
Self-administration of the drug is not recommended to prevent a possible deterioration of the patient's condition, since an overdose is likely the manifestation of some signs of poisoning with the active substance. And although the components of the drug are rapidly eliminated from the body, the recommendations of the accompanying instructions should be followed and the remedy taken in accordance with the prescribed treatment regimen.
Dosage forms
In pharmacies Clemastine is offered as a syrup, solution for injections and in the form of tablets.
- The solution should be used for the most targeted exposure and in particularly advanced stages of the disease. The injection allows to obtain the expected effect, to remove the most serious manifestations of allergy and to stabilize the patient's condition.
- Tablets sold in a polymer blister for 10 pieces, the dragees themselves are rounded, covered with a white soluble coating. Blisters are in a cardboard box, which also contains detailed instructions for the use of the drug.
- The syrup is offered for sale in a bottle of dark glass, it is most often prescribed for use by children: this form is easiest to use, children like.
Composition Clemastine
The main active substance of the drug under consideration is clemastin, which quickly penetrates into the skin with blood flow, eliminating itching, burning of the skin, its increased sensitivity. In 1 tablet Clemastine contains 1 mg of active ingredient.
Prices
The cost of the drug is quite democratic, the packaging of tablets has a price from 116 to 220 rubles.
Pharmacological action
The speed and multifaceted effects of Clemastin are explained by its balanced composition. Rapid absorption of the walls of the stomach with the intake of syrup or tablets, as well as the ingestion of the active substance into the bloodstream, gives a pronounced result after 2-5 hours from the moment of taking: allergic manifestations are eliminated, subjective manifestations are eliminated and the general well-being of the patient is improved.
With regard to the group of antiallergenic drugs, Clemastin copes well with such lesions, which are accompanied by severe allergy symptoms: itching, burning of the skin, increasing the degree of its sensitivity, the appearance of skin rashes and skin flushing. Using Clemastin in the complex treatment of allergies, you can as quickly as possible to achieve the expected result and maintain skin health.
Farmakodinamika
With its antipruritic effect, the preparation under consideration copes with frequent urge to sneeze, eliminates the increased release of mucus from the nasal passages, reduces the permeability of the walls of the capillaries. Due to rapid penetration into the bloodstream, the fastest decomposition of the nose is ensured( nasal passages are blocked).
Due to a decrease in vascular permeability, the edema of tissues is prevented, and H1 receptors are blocked. There is a small sedative effect that does not affect the degree of concentration of the patient, which allows the drug to be taken even by vehicle drivers and those whose activities are related to the management of complex mechanisms.
Clemastin Aktavis( photo)
Pharmacokinetics
Absorption of the active substance occurs after a short time from the moment of taking the remedy, and the effect comes in 30 minutes: the itching and burning of the epidermis, reducing the hypersensitivity of the skin. By binding to 95% of the blood proteins, the active substance enters the necessary areas, reacting with the H1 receptors and blocking them.
The elimination period consists of two phases, the second terminates after 5-6 hours;the decay products are produced by the kidneys( liquid phase).Disintegration occurs in the liver cells to the components, which are then easily removed and completely eliminated from the body. Even with prolonged use of the drug, there is no accumulation of its constituents in the tissue cells.
Indications
Indications for the admission of Clemastine include those conditions that are accompanied by swelling of the skin, its redness, the appearance of severe itching, burning, hypersensitivity. Any skin lesions having these manifestations are excellent for treatment with Clemastine, provided there are no contraindications to its use. However, there are relatively few situations and conditions of the organism that exclude the possibility of prescribing this antiallergic agent.
For diseases that respond well to healing with Clemastine, the following should be considered:
- allergic dermatitis;
- urticaria;
- atopic dermatitis;
- oral dermatitis;
- the first manifestations of psoriasis;
- eczema of any nature, incl.varicose on the legs;
- allergic rhinitis;
- bites bloodsucking insects.
The listed conditions one of the manifestations have pronounced itching and burning of the skin, which are perfectly removed using the Clemastine.
Instruction for use
Thanks to the detailed instructions accompanying the preparation in any dosage form, it is possible to determine the necessary dosage for removing the most characteristic manifestations of the diagnosed disease. However, in order to obtain the best effect, you should first make a diagnosis and then, with the help of a dermatologist, make the necessary treatment regimen.
Differences in the use of the drug in different dosage forms imply a different dosage when used by adults, children and pregnant and lactating women.
Adults
For the treatment of allergic forms of the disease, dosage is applied from 1 to 3 tablets during the day, which are consumed by water regardless of the time of ingestion. Preferably use this medication before eating.
The number of tablets taken can vary from the weight of the affected individual;the average rate is about 0.025 mg per 1 kg of the patient's weight. If the body does not accept the drug, stop using it or replace it with a similar one.
The injections can be administered intramuscularly and intravenously. The choice of the type of administration is determined by the attending physician-dermatologist in accordance with the severity of the manifestations of the disease, the duration of its course. The contents of the ampoule before the injection is dissolved in isotonic solution at the rate of 1 ampoule of substance per 10 ml of solution.
For Babies and Newborns
For children, a dose is used that is 2 times less than in adults: no more than 0.012 mg of substance should be delivered per kg of body weight of the child. Dosage is 0.5-1 tablet a day before meals.
A newborn drug can be given at a reduced dosage under the supervision of a doctor. Children are more suitable for use this drug in the form of syrup.
In pregnancy and lactation
During pregnancy, Clemastin can not be used because of the penetration of the active substance through the placental barrier. Only a doctor can determine the degree of necessity of taking the drug in pregnancy - exceeding the positive result for a woman in comparison with the likely negative impact on the fetus.
In a small percentage of the penetration of breast milk, the active substance Clemastin can be found in the body of the child, therefore, during breastfeeding it is recommended not to use the drug to treat allergic diseases.
Contraindications
For conditions in which Clemastin is not recommended, include increased sensitivity to constituents, exacerbation of existing symptoms, and severe renal failure, which may become more serious with this antiallergic agent.
Also to contraindications to the use of Clemastine are the following situations:
- prostate adenoma with the formation of nodules;
- glaucoma, in which bluish clouding of the lens is noted;
- peptic ulcer in the advanced stage of the course;
- lesions of the thyroid gland;
- high blood pressure, which persists for a long time.
These situations are contraindications to the use of Clemastine.
Side effects of
Use of the drug in question can lead to constipation, the appearance of severe dryness of the mucous membrane of the eyes, changes in tasty sensations during eating. There may also be negative symptoms such as dry mouth, poor urine separation, dizziness and nausea, as well as the urge to vomit, nasal obstruction, frequent urination.
Special instructions
- When using Clemastin in old age, an increase in the number of adverse events is likely, accompanied by abundant phlegm in the lungs, impaired vision.
- After 55 years, this drug should be used only as a syrup or tablets( use in the form of injections should be completely ruled out).
- In the treatment Clemastin should completely abandon the use of alcoholic beverages, since ethyl alcohol makes it difficult to absorb the active substance.
Interaction with other drugs
In the complex treatment of allergic manifestations, the Clemastin drug increases its effect, which allows it to be prescribed together with drugs of similar effect on the body. However, the interaction of the drug with monoamine oxidase inhibitors should be completely ruled out.
The use of opiates, sedatives and alcoholic beverages of any degree of strength reduces the strength of the Clemastine effect.
Reviews
Clemastin, a member of the group of antihistamines with a wide spectrum of action, perfectly removes the most severe manifestations of allergic reactions. This is evidenced by the numerous positive reviews of those who have already used this tool to treat allergic manifestations and symptoms of skin diseases.
Many also indicate the convenience of use, and the choice of the dosage form of the device makes it possible to choose exactly this method of influence, which will have a more positive effect on the patient's body. Even with a relatively small dosage of the remedy, there is a rapid improvement in the general condition of the patient, rapid removal of the main symptoms and elimination of unpleasant manifestations of allergy.
Analogs
To drugs with antihistamine and antiallergic effect of a similar nature, the following should be attributed:
- Tavegil;
- Loratadine;
- Braveligil;
- Rivtagil.
When comparing Clemastin and Tavegil, many users note the great efficacy of Clemastine in advanced stages of skin lesions, when it is required to eliminate such manifestations as severe itching, a significant increase in the sensitivity of the skin. In comparison with this drug against allergies, Loratadine, considered one of the most effective modern antihistamines, can be almost completely similar in its effect: quickly eliminating the main manifestations of allergy, Loratadin has a relatively small number of contraindications. However Clemastin gives a more pronounced result when using it in complex treatment.