Triderm is a dermatological agent for external use. The use of the drug is based only on the treatment of a disease obtained by a secondary infectious method. For preventive purposes, the agent is not used due to the intensive action of the active ingredients in the formulation. Effective in viral, fungal and bacterial infections, as well as in mixed genesis.
Features of the drug
Dosage forms and prices
Modern pharmaceuticals have not yet developed gels or Triderm shampoos with a similar medicinal effect, like the cream and ointment, which are currently the main forms of the drug Triderm.
- Cream and ointment Triderm are available in aluminum tubes weighing 30 grams( 15 grams).Tubes are packed in white paper packaging paper with the name of black color and a trade mark of the developer.
- The cost of Triderma( ointment) does not exceed 700 rubles per tube from 15 g. The cost of the cream is approximately below the ointment by 50 rubles.
Tridentum
Triaderm Ointment contains 0.001 g of gentamicin antibiotic, 0.01 g of antimicotic clotrimazole, 0.0005 g of anti-inflammatory agent betamethasone per 1 g of ointment. In addition to the basic substances, to strengthen the medicinal properties and make the necessary consistency for the ointment, the preparation is supplemented with paraffin in liquid and soft form.
Triderma Cream contains the same active ingredients as the ointment, but in a different quantitative composition. For creamy consistency, other auxiliary substances will be required: propylene diol, highly diluted phosphoric acid solution, phenylcarbinol, petrolatum, double dihydrophosphate sodium crystalline hydrate, liquid paraffin, macrogol cetostearate, alcoholic cetostearin derivative.
Pharmacological action
Pharmacodynamics
Integration of antibacterial properties Gentamycin, a substance of Betamethasone that eliminates allergic reactions, swelling, inflammation and preventing the formation of exudate, Clotrimazole with antifungal effect provides effective treatment of the pathologies shown. Microscopic pathogenic fungi of the genera Malassassia, Epidermophyton, Microsporium, Candida, Trichophyton have ergosterol as a part of the cell wall. Thanks to Clotrimazole, the synthesis of the ergosterol peptide is disrupted and the proliferation of fungal cells becomes difficult.
Pharmacokinetics
No data are available on intermediates, methods for their removal and bioavailability of the components of the drug delivered through the skin.
Indications
The effectiveness of the "Triderm" is revealed in the treatment of dermatological skin pathologies that occur with complications of an infectious, inflammatory and other nature. The most successful for the treatment of dermatitis are several varieties: atopic, allergic, simple. The presence of an antifungal component in Triderma allows you to fight with dermatomycosis( simple chronic and colorful lichen, candidiasis, lesions by dermatophytes).
The effectiveness of the external preparation in the treatment of various forms of eczema, auto-allergic pathology - limited neurodermatitis is proved.
Instruction for use
Dermatological Triderm is recommended exclusively as an external use. The reason for purchasing the ointment is the appointment of a doctor. Application cream or ointment is made by light rubbing movements in the affected area of the skin. The frequency of application of the cream on the skin - twice a day, in the morning and before going to bed.
Usually recovery with proper diagnosis occurs within 2-3 weeks or earlier. If after this period the stage of remission does not occur, a diagnostic examination should be performed to clarify the diagnosis. The patient should not take breaks in treatment if the doctor shows the use of the drug according to the instructions.
Contraindications
The use of Triderma should be under the constant supervision of a physician during the first three months of pregnancy, in preschool children and patients with occlusive dressings. Medical control in treatment with Triderm will be required in case of extensive skin lesion and broken integrity of deep layers of skin.
Do not use Triderm when:
- is not intolerant to certain active ingredients or excipients of the external agent;
- wound damage to the skin( in the open frame);
- childhood less than 2 years;
- herpes lesions of the skin;
- skin symptoms of syphilis;
- acute period of chicken pox;
- skin effects of vaccination;
- cutaneous tuberculosis.
Side effects of
The effects of incorporating an antibiotic in an external remedy sometimes appears as a skin rash or itching. Treatment in this case is not interrupted. After Clotrimazole component, individual patients may experience reddening of the skin at the site of application, exfoliation of the upper epidermis, increased hydration, blistering, slight tingling, itching, puffiness, irritation and urticaria.
- Local reactions of to Betamethasone contained in Triderma can be the formation of acne, increased hair formation, a decrease in melanin contained in the epitheliocytes, burning sensation, itching, allergic dermatitis formed during contact with the drug, folliculitis, maceration, striped atrophodermia, secondary infection.
- The general local reactions of to the drug are rare: melanin deficiency, itching, redness, exudation, tingling and burning sensation in the area of Triderma.
Special instructions
Triderma does not abruptly discontinue use: first, the application regimen is cut to once a day, in the next few days the drug is applied to the skin every other day, etc. In the ophthalmic practice, Triderm is not prescribed and is not suitable for self-administration.
The cases of development of resistance of some pathogenic bacteria to Triderm's effect are noted with prolonged exposure to one of the components of the preparation - Gentamicin. The combined use of aminoglycoside antibacterial agents with Gentamicin Triderma is sometimes manifested by allergic reactions.
Dependence of concentration of attention in the management of vehicles from the use of Triderma is not revealed.
Interaction with other medicinal substances
Except for the joint use of Triderm as an antibacterial agent with other antibiotics, when adverse allergic reactions can be detected, no other complications of drug interactions have been detected.
Reviews
Nine out of ten patients who used Triderm's external remedy left positive comments about the drug. The remaining 10% of patients who noted the negative effect of Triderm use were divided into 2 groups: those using the drug without a doctor's prescription and undesirable side effects.
Analogues of
The list of analogues of Triderma depends on the produced dosage form: in Triderm cream analogues - Triacutan, Lokoid, Dermokas, Triacutan. For Tridentum ointment, you can find a similar substitute in the form of Diprosalik, Belosalik and Acriderm GK.
About Triderm in detail will tell this video: