Paracetamol tablets in the treatment of headaches

1 Pharmacological action of

Paracetamol is able to exert anti-inflammatory, antipyretic and analgesic effect. The mechanism of its influence is based on inhibition of the synthesis of prostaglandins, by suppressing the center of thermoregulation in the hypothalamus. Tablets have the property of completely absorbed into the digestive system. Within half an hour the result becomes noticeable. The duration of the action lasts about 3-4 hours.

Paracetamol tablets are characterized by low anti-inflammatory activity, depriving them, in contrast to non-steroidal anti-inflammatory drugs, side effects such as irritation of the gastric mucosa or a violation of the water-mineral balance.

In its safety, the use of paracetamol from the head as an analgesic is very good. The truth of the positive result will be seen in the event that the correct rate of consumption is observed. This is due to the correct dose and the duration of the drug. Side effects are rare, but they do exist. It can be allergic reactions, disorders in the circulatory system and in the work of the liver and kidneys.

The effectiveness of paracetamol is in a properly selected dose, and not in the manufacturer or bright packaging.

Buying paracetamol from a headache in a pharmacy, you can face a lot of analogues. The difference in price will often be significant. In addition to the usual tablets, liquid medications have been developed. It can be syrups, solutions, soluble powders and candles. Liquid preparations should be slightly warmed up to a state corresponding to body temperature. This will allow them to better assimilate and give the opportunity to have a quick positive effect. Often, the doctor appoints children to use candles for the night. Candles have not so active properties, as all those preparations that are used inside. Therefore, they are used at low temperature. Introducing suppositories rectally, it should be remembered that a single dose is also a high rate, at the rate of 20-25 mg / kg. It is worth remembering that the higher the body temperature, the slower the absorption of the drug into the intestine will occur.

Paracetamol therapy can be of great help when a viral infection is present in the body. But he will not be able to prove himself in the same way with bacterial infections.

Taking paracetamol from the head or as a febrifuge, we completely forget that it is able to eliminate toothache, neuralgia( pain attacks in the affected nerve zone), myalgia( muscle pain), migraine, pain with injuries and burns.

2 Methods of application

Since paracetamol is an antipyretic and analgesic drug, it is often prescribed by doctors even to infants. However, it is necessary to adhere to the following application rules developed by the World Health Organization:

• if the child is not yet 2 months old, the use of antipyretic drugs is allowed at a temperature of 38.5 degrees;
• if the child's age has exceeded 2 months, the antipyretic solution is allowed at a temperature of 39 degrees.
• if a child over 2 months of age becomes visible slight convulsions, immediately you need to bring down the temperature even at 38 degrees.

When children reach the age of 3 months, it is allowed to take a suspension, the dosage of which is determined by the attending physician. Rectal suppositories are prescribed from the age of three. Admission of pills is allowed only adults and adolescents. The duration of treatment should not exceed one week.

3 Contraindications and overdose

Contraindications may be with hypersensitivity to any component included in the preparation. Do not use paracetamol in the following cases:

• if there are violations of the liver and kidneys in the body;
• for blood diseases;
• in phenylketonuria( a disease of the nervous system that occurs when an amino acid metabolism is disturbed);
• with alcoholism, otherwise it will intensify the hepatotoxicity of tablets;
• with severe anemia, etc.

One should be careful in taking the drug during pregnancy and lactation, as it is able to penetrate into breast milk in an insignificant amount. It should be used with accuracy in case of headaches and elderly people.

Paracetamol does not treat, but only dulls the severity of a particular symptom.

Paracetamol administration affects the results of uric acid and glucose testing. In the appointment of paracetamol, monitoring of the picture of peripheral blood and the functional state of the liver is important. Liver damage in an adult can occur with the intake of more than 10 grams of the drug, and in children it can occur if the suspension or syrup exceeds the size of 150 mg / kg of the child's body weight.

A high dose of paracetamol can cause disorders in the central nervous system, which will not remove, but only add nervousness, anxiety, dizziness. Each organism reacts differently. Sometimes an overdose manifests itself in the violation of the heart rate, sweat may become more intense, the susceptibility of the surrounding environment may worsen, nausea and vomiting may occur. In large doses, the body will begin to sense the presence of the toxic effect of this medication, which in time will manifest itself in the defeat of the kidneys.

If an overdose occurs, you should immediately contact an ambulance. Before the arrival of a doctor, you can provide first aid at home. Activated carbon will become an assistant. But this method can only help if the overdose was committed within one hour. Rinsing the stomach with water with a weak solution of soda will slightly ease the condition of the victim. Check the concentration of paracetamol in the blood is possible only after 4 hours after the application of the drug.

Paracetamol is able to interact with certain drugs. For example, its use together with preparations containing metoclopramide or domperidone, accelerates the absorption of paracetamol. And the use of cholestyramine - on the contrary blunts. It is always necessary to get acquainted with the annotation of any medical product so as not to get trapped. So whether paracetamol helps your body, judge only by yourself!

4 Available analogues of the preparation

It is possible to eliminate the headache without paracetamol, and with the help of other tablets. But always consider what contraindications they have. The replacement of paracetamol may be analgin( analogues of which in turn may be citramone, tempalgin, pentalgin).But it is not recommended for renal and hepatic insufficiency, hypotension and other diseases. Aspirin is a common remedy for the removal of headaches, and it also has the property of diluting blood. But it negatively affects the gastrointestinal tract. Ibuprofen( or its analogs - nurofen, ibuklin) is a good antipyretic and analgesic, but with its contraindications. It can not be taken with kidney disease, liver, and ulcers.

Like many other medical products, paracetamol is produced both in pure form and combined with various anti-cold medications. Their differences can be in the producer and in the price. Here are some of them:

1. Gripex( tablets).
2. Dapheron( one tablet contains 500 mg of paracetamol).Produced in the form of tablets and suspensions.
3. Children's panadol( suspension).
4. Coldrex( tablets, powders).They have a complex effect for headache and colds.
5. Milistan. Produced in the form of tablets and syrup.
6. Panadol Active. Tablets that have an antipyretic and analgesic effect.
7. Piaron. They have an analgesic and antipyretic effect.
8. Rapidol. It exists in the form of tablets and rectal solution.
9. Solpadeine. It has analgesic effect.
10. Teraflu is a complex remedy for colds and headaches.
11. Efferalgan. Produced in the form of tablets, as well as solution.

All of the aforementioned agents include paracetamol and other excipients. Admission of any drug for headaches should in no case be delayed for a long time. This can be addictive. Consultation of a doctor will always help in the proper selection of medicines suitable for your body.