Not the last place among pathological lesions of the mucous and deep tissues of the stomach is occupied with medicinal ulcers. They are caused by ulcerogenic preparations, among which the most common are indomethacin, aspirin, brufen, diclofen, potassium chloride, nonsteroids, sulfonamides and a number of others. Most often, the onset of the disease occurs after long-term use of tableted drugs, especially in large doses.
A drug ulcer is formed in different ways. Some drugs can inhibit the production of protective hormones-prostaglandins, resulting in reduced production of gastric mucus. Others themselves have a negative effect on the walls of the muscle sack. Still others provoke a significant increase in the pH level due to increased formation of hydrochloric acid by the covering cells. And under the influence of glucocorticosteroids, the secretory functions of pepsin and gastrin are increased, due to which the aggressiveness of the contents of the stomach increases several times.
In some cases, drug-induced gastric ulcers heal on their own after the withdrawal of the drug-provoking drugs. But complications often occur. That is why any medicines should be taken only on the advice of a doctor and after carrying out the appropriate examinations.
Ulcer and aspirin are mutually exclusive concepts of
Because aspirin is one of the most commonly used drugs, cases of aspirin ulcer are very common. Her symptoms are virtually indistinguishable from signs of illness caused by other causes. Among them:
- pain in the epigastric region;
- nausea, accompanied by vomiting after eating;
- hiccups;
- diarrhea.
In case of such negative factors, the drug should be discontinued.
As a rule, after taking the medicine, the aspirin ulcer of the stomach passes by itself. But also for a speedy recovery can be prescribed gastroprotective drugs or medicines of the IPP group.
Naturally, aspirin in the stomach ulcer is strictly prohibited. Acetylsalicylic acid can cause not only painful sensations, but to provoke internal bleeding and even perforation of the walls. To reduce the negative impact of aspirin, experts advise abundantly to take a pill with milk. But in no case should you take the drug on an empty stomach or in combination with alcohol( alcohol tinctures).