Drug pancreatitis, as a disease, is known relatively recently, since the second half of the last century. It was at that time began to appear reports of pancreatic diseases of varying severity, the cause of which was the use of medications.
Most often, it was about corticosteroid drugs used to treat severe forms of rheumatism, bronchial asthma, aplastic anemia and a number of other diseases. The first cases of symptoms of drug pancreatitis have been described in the development of pancreatic lesions in the form of hemorrhagic with a lethal outcome just after taking corticosteroid drugs.
In this case, the drug pancreatitis was diagnosed in children taking corticosteroids, for which the development of pancreatic necrosis is uncommon in normal conditions and practically does not occur.
The severity of the disease in many ways depended on the duration of the drug and the dosage used. Some patients experienced allergic reactions, as well as steroid diabetes and fibrosis.
In further studies, cases of development of drug pancreatitis caused by a number of other pharmaceutical preparations, including tetracycline, clonidine, paracetamol, and many others, have been identified, which confirmed the initial assumption of the detrimental effect of a number of drugs on the functioning of the pancreas.
When diagnosing drug pancreatitis, the appearance of painful sensations in the left epigastric region is observed almost immediately after taking the drugs. The disease develops as a hemorrhagic pancreatitis. With lighter forms of the disease develops acute or chronic pancreatitis.
When diagnosing, it is very important to reduce symptoms and their complete disappearance when taking drugs and repeat the clinical picture when they resume treatment.
In the treatment of pancreatitis caused by medication( even if it is only a matter of suspicion), it is necessary to cancel the prescribed drug and do not use it anymore. The patient is shown hospitalization and usual therapy, used in the treatment of acute and chronic pancreatitis.
The choice of treatment depends on the severity of the course of the disease and the severity of the process. When prescribing a particular drug, it is necessary to take into account the condition of the patient's pancreas, his heredity and previous illnesses.