Solcoseryl has found itself in pharmacological practice as a means to accelerate metabolic processes, improve the supply of nutrients and restore damaged cellular tissue elements. And today we will review the instructions for use and prices for Solcoseril ointment, reviews about it and analogues of the drug.
Features of the drug
The Swiss drug has not been distributed in Western countries, Japan, the state structures of the Americas for several reasons: unusual composition, lack of clinical trials, etc.
The features and properties of the drug Solcoseryl will tell this video:
Composition
Solcoseryl contains the main activesubstance - hemodializate calves up to 3 months, released from blood plasma and devoid of complex protein complexes. Hemodialysate is obtained by centrifuge action on the calf plasma obtained. Centrifugation can separate high molecular proteins, so hemodialysis is called deproteinized.
The molecular mass of the plasma residue after centrifugation is 5,000 daltons. The chemical composition of dialysate includes low-molecular substances: dipeptides, amino acids, complexes of proteins with carbohydrates, remains of blood elements, nucleosides.
Dosage Forms
Solcoseryl is represented by several dosage forms, the prevalence and concentration of which is varied, which is the reason for the variability in cost.
- The cheapest drug is Ointment Solcoseryl 5% concentration. On the Internet and city pharmacies the average cost per ointment is 200 rubles. The gel dosage form of 10% concentration is the same as the ointment. Gel for ophthalmology 20% concentration is 1.5 times ointment and 10% gel - 300 rubles.
- Solution for injection is packed in ampoules of 2ml, 5ml and 10ml. Packages can contain from 5 to 25 ampoules. Solution for injection in ampoules of 5 ml and 5 pieces in a box is sold starting from 750 rubles. Packing of 25 ampoules of 2 ml will cost over 1500 rubles.
- Dragee Solcoseryl is manufactured by Swiss pharmacists at 0,04 g of 20 pieces per pack. Known tablets of 0.1 and 0.2 grams. All tablets are not purchased by the Russian Federation, so Russians can not buy this form of Solcoseryl at home.
- The latest form of Solcoseryl - dental adhesive paste , used in dentistry, costs approximately 350 rubles in the pharmaceutical market. The paste is packed in tubes with a mass of 5 grams.
Pharmacological action
Farmakodinamika
Solcoseryl enhances the healing process in tissues. With the help of the drug, there is an increase in the supply of oxygen to those cells that are deficient in it. Intracellular formation of ATP increases.
The share of intracellular decomposition of substances with the participation of oxygen, oxidative phosphorylation increases, the process of repairing damaged cells is enhanced. The formation of mature fibroblasts and collagen of the vascular endothelium increases.
Pharmacokinetics
Due to the biogenic origin of the main component of Solcoseryl( constituent parts of the blood), it is not possible to determine the half-life of the compounds, their metabolic pathway, the process of excretion of their compounds. The reason is the presence in the blood of the same chemicals that are without the introduction of the drug in a smaller amount.
Metabolism of the injected drug and natural substances occurs by a single mechanism, so the intermediate metabolism substances in the biopsy are not grounds for distinguishing when the drug is administered or not. The only information is about the beginning of the drug after taking 10 minutes after the injection. The duration of the drug is about 3 hours.
Indications
- Solcoseryl is effective in pathologies of the vascular bed to the central nervous system and peripheral parts of the human body. Their peripheral disorders of blood flow are chronic pathologies of venous circulation, leading to a disruption in the nutritional process of tissues.
- It makes sense to prescribe the drug in case of obstruction of the vessels during the defeat of the vascular walls.
- Solcoseryl is effective in all types of vascular impairment of blood supply to areas of the brain and spinal cord( ischemic and hemorrhagic strokes).
- The drug is prescribed after the receipt of craniocerebral trauma.
- The gel and ointment forms of Solcoseryl are effective for skin lesions( wounds, abrasions, scratches, frostbite and burns of 1 and 2 degrees, chemical burns( alcoholic gastritis)
- The drug is also used if the patient has radiation dermatitis, dyshidrotic eczema.on the use of the gel Solcoseryl
About the indications for the use of Solcoseryl will tell this video:
Instructions for use Solkoserila
- As injections, Solcoseryl solution is administered by intramuscular injection of 2 ml per dayand the course of treatment is 20 days
- If the patient's health and medical conditions allow, intravenous drip of the drug is prescribed at a rate of 250 ml per day for 3 weeks
- Depending on the type of disease, the doctor can prescribe a dosage of 20 and 25ml, dissolving the preparation in isotonic solution. The speed of drip infusion is adjusted to 20-40 per minute
When topical application is recommended, first use the gel Solcoseryl, applying a thin layer on the damaged surface. The gel should be used three times a day until the wound is no longer wetting. From this period, go to the ointment, applying it one( two) times a day. When the regeneration processes slow down, the skin returns to the gel base.
Contraindications
- All dosage forms of Solcoseryl are contraindicated in people with an identified intolerance to the components of the drug.
- Solutions for intravenous drip and jet infusion, intramuscular injections are contraindicated in patients younger than 18 years of age.
Side effects of
Allergic reactions in the form of itching, focal reddening of the skin, marginal dermatitis and a sharp manifestation of sensitivity to the drug are not excluded when using Solcoseryl.
There may be a burning sensation in the area that has undergone gel application. If you have an unpleasant symptom, Solcoseryl should be discarded.
Specific instructions
Evidence base of possible harm Solcoseryl for children's body in the form of ointment and gel is absent. Solutions for parenteral administration for under-aged patients are not prescribed. Treatment of severe forms of diseases allows the use of a combination of intravenous injections and Solcoseryl external agents simultaneously.
Treatment of wounds involves pre-treatment with antiseptic solutions, washing, and subsequently applying gels or ointments. Caution is used infusion infusions in patients with congestive pulmonary and cardiac activity, oliguria, anuria, etc.
Interactions with other drugs
- When administering the drip infusion Solcoseryl solution, it should be mixed with only 5% glucose solution or 0.89% sodium chloride solution.
- Drip injections of the drug should not be mixed with the simultaneous infusion of the extract of Ginkgo biloba, benzyclan fumarate and naphthydrofuryl.
Reviews
Reviews left by patients after all forms of Solcosernil, only positive. It indicates the rapid healing of trophic ulcers, burns, skin wounds.
Patients are delighted not to leave scars after application. The rapid action of the eye gel, an analgesic and healing effect after the dental adhesive paste is noted.
Analogs
- The only analogue of Solcoseryl for injection is Actovegin, which is similar to the chemical composition and method of preparation.
- Eye gel has the largest number of analogues: Taufon, Glemichen, Difislez, etc. Ointments with a similar effect are known as Sagenite, Redecila, Evista, etc. The analogue of Solcoseril gel is Actovegin.
- Similar properties with Solcoseril are also shown by Levomekol.